This document provides guidelines for communities interested in developing public cholesterol education and screening programs. It contains information to use in considering a program and protocols to follow in conducting a program that meets standards established by the National Cholesterol Education Program. An introduction summarizes content. Section 2 covers five topic areas of concern: (1) the goal and objectives of public cholesterol education and screening; (2) general recommendations for program development; (3) questions to ask before becoming involved with public cholesterol education and screening, including liability, staff, medical community links, screening site, quality control, and portable analyzers; (4) portable analyzer comparison; and (5) statement on cholesterol screening of children. Section 3 details the steps involved in performing the actual procedure on the day of screening and education. Three stations at the screening site are described: registration, measurement, and education and referral. Concerns, materials, setup, and procedure are detailed for each station. Quality control procedures are outlined. Photo-ready copies of forms and additional education materials include informed consent, education message, medical care referral information, follow-up reminder letter, basic definitions, commonly asked questions, and annotated bibliography of 48 recommended materials and resources. The final section lists eight suggestions for program evaluation. (YLB)