The procedure of a physical chemistry experiment for university students must be designed in a way that the accuracy and precision of the measurements is properly maintained. However, in many cases, that requires costly and sophisticated equipment not readily available in developing countries. A simple, low-cost experiment to determine isobaric…

Gaming, an integral part of many students' lives outside school, can provide an engaging platform for focusing students on important disciplinary core concepts as an entry into developing students' understanding of these concepts through science practices. This article highlights how S'cape can be used to support student learning aligned with the…

The classic experiment presented in this problem-solving test was designed to identify the template molecules of translation by analyzing the synthesis of phage proteins in "Escherichia coli" cells infected with bacteriophage T4. The work described in this test led to one of the most seminal discoveries of early molecular biology: it dealt a…

Mutational inactivation of a specific gene is the most powerful technique to analyze the biological function of the gene. This approach has been used for a long time in viruses, bacteria, yeast, and fruit fly, but looked quite hopeless in more complex organisms. Targeted inactivation of specific genes (also known as knock-out mutation) in mice is…

Comprehensive measurement of gene expression using high-density nucleic acid arrays (i.e. microarrays) has become an important tool for investigating the molecular differences in clinical and research samples. Consequently, inclusion of discussion in biochemistry, molecular biology, or other appropriate courses of microarray technologies has…

Describes an exercise designed to be used in an Advanced Placement (AP) chemistry course to accompany the study of thermodynamics. Uses Differential Scanning Calorimetry in teaching the concepts of thermochemistry and thermodynamics. (JRH)

Discusses the use of student-generated rubrics in science classes where students design their own laboratory activities to solve open-ended problems. Promotes careful consideration of what constitutes open-ended work. Presents certain rubrics and grading criteria. (JRH)

Reexamines an experiment in which the volumetric fraction of oxygen in air was supposed to have been determined. Presents challenges to the procedure. (DDR)

Describes how Newton's Law of Cooling and the Method of Mixtures are used to solve the basic dilemma of whether to add the cool cream to the hot coffee or to let the black coffee cool down first and then add the cream. (ZWH)

Presents a six-step problem-solving process which the author has used to present creative science investigations to fourth, fifth, and sixth graders. (Author/SJL)

Explores strategies in the situation of a runner trying to evade a tackler on a football field. Enables the student to test intuitive strategies in a familiar situation using simple graphical and numerical methods or direct experimentation. (JRH)

Presents problems appropriate for high school and college students that highlight dilution methods. Promotes an understanding of dilution methods in order to prevent the unnecessary waste of chemicals and glassware in biology laboratories. (JRH)

Describes a physics experiment which demonstrates the pitfalls of assuming that a model which represents an ideal system is applicable to a real experiment. Explains how the failure may give greater understanding of the problem and may lead to improvements in the model. (ML)

Described is a laboratory activity to determine five unknown organic compounds. The procedures are designed to help students determine unknowns from a series of tests. (RH)

Described is an experiment that uses nuclear magnetic resonance to study the anomalous paramagnetism of iron(III) chelates. (RH)