Describes an experiment on the use of problem-based learning. (Author/YDS)

Suggests that if students are to study enzyme kinetics they should do more than just gloss over the surface. Adequate time should be given for the student to thoroughly study the mechanisms to development a complete understanding. (MVL)

We describe an undergraduate laboratory experiment that combines the advantages of problem-based learning with the need for biochemistry students to become proficient in practical laboratory skills. It also avoids the need to obtain ethical approval for recruiting volunteers and eliminates any possible biosafety issues with the handling and…

In departure from the standard approach of using several problems to cover specific topics in a class, I use a single problem to cover the contents of the entire semester-equivalent biochemistry classes. I have developed a problem-based service-learning (PBSL) problem on HIV/AIDS to cover nucleic acid concepts that are typically taught in the…

Bioinformatics has emerged as an important research tool in recent years. The ability to mine large databases for relevant information has become increasingly central to many different aspects of biochemistry and molecular biology. It is important that undergraduates be introduced to the available information and methodologies. We present a…

Describes the implementation of the innovative Guided Discovery Curriculum at the National College of Chiropractic. Emphasizes the relevance of biochemical principles to clinical practice through the selection of two clinical cases. (DDR)

A protein lacking one of the 20 common amino acids is a protein lipogram. This open-ended problem-based learning assignment deals with the evolution of proteins with biased amino acid composition. It has students query protein and metabolic databases to test the hypothesis that natural selection has reduced the frequency of each amino acid…

Discusses experiences with the use of problem-based learning as applied to knowledge-rich biochemistry courses. Concludes that problem-based learning is not only effective in promoting habits of mind that support higher order thinking but also a powerful vehicle for conveying knowledge by imparting separate bits of knowledge as interconnected…

Describes an integrated problem-based learning experience for first-year medical students and assesses the effectiveness of the process in identifying basic science issues relevant to biochemical principles. (DDR)

Describes the design of a biochemistry course that uses problem-based learning. Provides opportunities for students to question, dispute, confirm, and disconfirm their understanding of basic concepts. Emphasizes self-correction through dialogue. Topics covered include amino acids, metabolic pathways and inherited disease, proteins, enzymes and…