Given the current trends of physical inactivity, overweight and obesity rates, and chronic disease prevalence, understanding appropriate levels of physical activity, healthful nutrition, and risk reduction for chronic-disease is crucial. The purpose of this study was to identify perceptions of the effectiveness of an online personal health and fitness course. As the prevalence of online education increases, pedagogies that enhance their effectiveness may be beneficial in reducing the rates of physical inactivity, obesity, and chronic disease. This study investigated the effectiveness of an online personal fitness course in terms of (a) meeting course objectives, (b) enhancing or modifying attitudes and choices related to physical activity, nutrition, and chronic-disease prevention, and (c) Moore's Theory of Interaction, Connectivism, and Andragogy. Study participants were enrolled in a post-secondary online personal fitness course. Data sources used were a survey instrument, students' written reflections, and pre- and post-class fitness-testing results. Survey results report most students (53.3%) achieved Almost All of the course objectives, while 20% achieved Several objectives and 16.7% achieved some. Survey results also show that as a result of learning in the class, most participants increased physical activity, most consciously made nutrition choices that met the dietary guidelines, and most considered the choices they were making and how those choices might affect risk for developing chronic disease. Written reflections analysis indicated that students were physically active throughout the course, even though the class did not meet face-to-face. A paired samples t-test indicated that pre- and post-fitness testing changes in the mile-run time, the cardiac-fitness level, the curl-up test, the push-up test and rating, and thigh flexibility were statistically significant at the specified 0.05 level. As the prevalence of online education increases, pedagogies that enhance effectiveness of such a course may be beneficial in reducing the rates of physical inactivity, obesity, and chronic disease. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]