The "Morbidity and Mortality Weekly Report" ("MMWR") series of publications is published by the Office of Science, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services. Articles included in this supplement are: (1) Overview and Methods for the Youth Risk Behavior Surveillance System -- United States, 2023; (2) Adult Caretaker Engagement and School Connectedness and Association with Substance Use, Indicators of Emotional Well-Being and Suicide Risk, and Experiences with Violence Among American Indian or Alaska Native High School Students -- Youth Risk Behavior Survey, United States, 2023; (3) Frequent Social Media Use and Experiences with Bullying Victimization, Persistent Feelings of Sadness or Hopelessness, and Suicide Risk Among High School Students -- Youth Risk Behavior Survey, United States, 2023; (4) Experiences of Racism in School and Associations with Mental Health, Suicide Risk, and Substance Use Among High School Students -- Youth Risk Behavior Survey, United States, 2023; (5) Adverse Childhood Experiences and Health Conditions and Risk Behaviors Among High School Students -- Youth Risk Behavior Survey, United States, 2023; (6) Disparities in School Connectedness, Unstable Housing, Experiences of Violence, Mental Health, and Suicidal Thoughts and Behaviors Among Transgender and Cisgender High School Students -- Youth Risk Behavior Survey, United States, 2023; (7) Asking for Verbal Sexual Consent and Experiences of Sexual Violence and Sexual Behaviors Among High School Students -- Youth Risk Behavior Survey, United States, 2023; (8) Report of Unfair Discipline at School and Associations with Health Risk Behaviors and Experiences -- Youth Risk Behavior Survey, United States, 2023; (9) Mental Health and Suicide Risk Among High School Students and Protective Factors -- Youth Risk Behavior Survey, United States, 2023; (10) Skipping Breakfast and Academic Grades, Persistent Feelings of Sadness or Hopelessness, and School Connectedness Among High School Students -- Youth Risk Behavior Survey, United States, 2023; and (11) Physical Activity Behaviors and Negative Safety and Violence Experiences Among High School Students -- Youth Risk Behavior Survey, United States, 2023.