The contemporary situation in the Baltic region, namely, the lack of working places due to the structural problems, a high unemployment rate, the migration of highly qualified people and the low rate of self-employees, demands on innovation as an engine of the economic development with a strong impact on sustainable development in the European Union. Clusters became a target for local and regional initiatives to promote competitiveness and job-creation. Cluster contributes to new and better jobs in new industries and offers potential solutions for the quality, maintenance and sustainable development of the economy in the European Union. Cluster is formed by the collaborative process based on mutual sustainability, complementarity and reflexivity. University in a cluster provides student engineers with the appropriate skills and competences for innovation and creates new knowledge within the "knowledge triangle" of education, research and innovation. The hypothesis for further studies is put forth. A bibliography is included. (Contains 2 tables, 3 figures, and a bibliography.)