This guide contains questions and answers about Section 508 of the Rehabilitation Act, as amended in 1986 by Public Law 99-506, which required the federal government to establish, in consultation with industry, guidelines to ensure that individuals with disabilities may use electronic office equipment with or without special peripherals. The guide explains how the federal government has changed its rules for purchasing or leasing information technology to comply with the law; examines the effect of Section 508 on states funded under Public Law 100-407, the Technology-Related Assistance for Individuals with Disabilities Act of 1988; explains how Section 508 is enforced; defines "electronic equipment accessibility"; outlines how the federal government decides what equipment to buy; notes equipment accommodations commonly used, such as alternative input, alternative screen display, alternatives to audible information, and development of local area networks; and offers sources for additional information. (JDD)