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Direct linkRowena Ng; Allison Kalinousky; Jacqueline Harris – Journal of Autism and Developmental Disorders, 2025
KAT6B and KAT6A belong to the MYST family of lysine acetyltransferases, and regulate gene expression via histone modification. Although both proteins share similar structure and epigenetic regulatory functions, it remains unclear if KAT6A/6B mutation disorders, both very rare conditions, yield the same neurocognitive presentation and thus benefit…
Descriptors: Genetics, Genetic Disorders, Symptoms (Individual Disorders), Neuropsychology
Pasquale Cardellicchio; Sara Borgomaneri – npj Science of Learning, 2025
The consolidation process stabilizes a new initially labile memory. This consolidation could operate on a shorter timescale during wakefulness after initial motor learning. Within micro-offline learning states, sequences of simple individual actions learned through interleaved practice are condensed into a unified skill through a time-dependent…
Descriptors: Brain, Brain Hemisphere Functions, Genetics, Cognitive Processes
Jana Runze; Marinus H. Van IJzendoorn; Annemieke M. Witte; Charlotte A. M. Cecil; Marian J. Bakermans-Kranenburg – JCPP Advances, 2025
Background: In their recent paper, Del Giudice and Haltigan argue that attachment in childhood and attachment representations in adulthood are influenced by the cognitive capabilities of children and parents, that would causally link parents' attachment states of mind to children's attachment. In the current pre-registered study, we empirically…
Descriptors: Attachment Behavior, Intelligence, Intelligence Quotient, Cognitive Ability
Latha Valluripalli Soorya; Camille W. Brune; Cristan A. Farmer; Edith V. Ocampo; Natalie I. Berger; Deborah A. Pearson; Robyn M. Busch; Patricia Klaas; Paige Siper; Kristn Currans; Amanda C. Gulsrud; Jennifer M. Phillips; Rajna Filip-Dhima; Sarah E. O’Kelley; Thomas W. Frazier; Tess Levy; Allison L. Wainer; Joseph D. Buxbaum; Craig M. Powell; Jonathan A. Bernstein; Simon K. Warfield; Darcy A. Krueger; E. Martina Bebin; Hope Northrup; Shafali S. Jeste; Alexander Kolevzon; Elizabeth Berry-Kravis; Mustafa Sahin; Siddharth Srivastava; Audrey Thurm – American Journal on Intellectual and Developmental Disabilities, 2025
The Developmental Synaptopathies Consortium is a multisite natural history network studying rare, neurogenetic syndromes associated with synaptic dysfunction and developmental delays. One aim of the Consortium is clinical trial readiness, including identifying clinical concepts and validating their measurement. We evaluated the scope and…
Descriptors: Intellectual Disability, Genetic Disorders, Neurological Impairments, Measurement Techniques
Lucía de Hoyos; Ellen Verhoef; Aysu Okbay; Janne R. Vermeulen; Celeste Figaroa; Miriam Lense; Simon E. Fisher; Reyna L. Gordon; Beate St Pourcain – npj Science of Learning, 2025
Early-life abilities involved in perceiving, producing and engaging with music (musicality) may shape later (social) communication and language abilities. Here, we investigate phenotypic and genetic relationships linking musicality and communication abilities by studying information from preschool and school-aged children of the Avon Longitudinal…
Descriptors: Music Education, Preschool Education, Preschool Children, Communication Skills
