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Direct linkDaina M. Tagavi; Yael G. Dai; Natalie I. Berger; Marisa Petruccelli; Sabine E. Scott; Devon Oosting; Mya Howard; Alice S. Carter; Brooke Ingersoll; Allison L. Wainer; Sarabeth Broder-Fingert; Wendy L. Stone – Journal of Autism and Developmental Disorders, 2025
COVID-19 required many research teams to shift from in-person to remote assessments, which posed both procedural and theoretical challenges. While research has explored the utility of remote assessments for autism diagnosis from the perspective of families and clinicians, less is known about their application in clinical trials. This paper…
Descriptors: Toddlers, Autism Spectrum Disorders, Randomized Controlled Trials, Clinical Diagnosis
Ryan J. Martin; Suzannah Iadarola; Rose Iovannone; Brenna Cavanaugh; Krystal Fontechia; Lynne Levato; Cynthia M. Anderson – Journal of Developmental and Physical Disabilities, 2024
Implementation of evidence-based practices for autistic students must be informed by robust research literature. Randomized-controlled trials (RCTs) are often considered a "gold standard" methodology for determining the effectiveness of interventions. However, the complex nature of schools presents challenges for implementing successful…
Descriptors: Autism Spectrum Disorders, Students with Disabilities, Intervention, Randomized Controlled Trials
Alexis M. Brewe; Ligia Antezana; Corinne N. Carlton; Denis Gracanin; John A. Richey; Inyoung Kim; Susan W. White – Journal of Autism and Developmental Disorders, 2025
Purpose: Many individuals with autism spectrum disorder (ASD) experience challenges with facial emotion recognition (FER), which may exacerbate social difficulties in ASD. Few studies have examined whether FER can be experimentally manipulated and improved for autistic people. This study utilized a randomized controlled trial design to examine…
Descriptors: Randomized Controlled Trials, Brain, Nonverbal Communication, Emotional Response
Cristina Vargas; Daniela Paoletti; Simona De Stasio; Carmen Berenguer – Autism: The International Journal of Research and Practice, 2025
Sleep disturbances are one of the most common comorbidities in autistic children and adolescence. Considering the impact of sleep disorders on development and daily functioning, it is important to know which treatments are considered effective in literature. This systematic review and meta-analysis study specifically aimed to investigate the…
Descriptors: Sleep, Children, Adolescents, Autism Spectrum Disorders
Jianjun Ou; Robert C. Smith; Russell H. Tobe; Jingjing Lin; Jen Arriaza; Jed W. Fahey; Ruiting Liu; Ying Zeng; Yanan Liu; Lian Huang; Yidong Shen; Yamin Li; Daomeng Cheng; Brian Cornblatt; John M. Davis; Jingping Zhao; Renrong Wu; Hua Jin – Journal of Autism and Developmental Disorders, 2024
Sulforaphane has been reported to possibly improve core symptoms associated with autism spectrum disorders from mostly small size studies. Here we present results of a larger randomized clinical trial (N = 108) in China. There were no significant changes in caregiver rated scales between sulforaphane and placebo groups. However, clinician rated…
Descriptors: Drug Therapy, Outcomes of Treatment, Autism Spectrum Disorders, Randomized Controlled Trials
Lucy Beasant; Alba Realpe; Sarah Douglas; Lorcan Kenny; Dheeraj Rai; Nicola Mills – Autism: The International Journal of Research and Practice, 2024
The purpose of this study is to explore the views of autistic adults on randomised controlled trials, specifically on processes such as randomisation and blinding, to understand the barriers and facilitators for recruiting autistic people to randomised controlled trials involving medications. We conducted one-to-one interviews with 49 autistic…
Descriptors: Autism Spectrum Disorders, Adults, Attitudes, Randomized Controlled Trials
Amanda Timmerman; Vasiliki Totsika; Valerie Lye; Laura Crane; Audrey Linden; Elizabeth Pellicano – Autism: The International Journal of Research and Practice, 2025
Autistic people are more likely to have co-occurring mental health conditions compared to the general population, and mental health interventions have been identified as a top research priority by autistic people and the wider autism community. Autistic adults have also communicated that quality of life is the outcome that matters most to them in…
Descriptors: Adults, Autism Spectrum Disorders, Quality of Life, Randomized Controlled Trials
Laura Graham Holmes; Leona M. Ofei; Megan H. Bair-Merritt; Pamela L. Palmucci; Emily F. Rothman – Review Journal of Autism and Developmental Disorders, 2022
Background: This systematic review investigated the state of intervention science on programs that promote healthy intimate relationship skills and sexual health for autistic youth (i.e., healthy intimacy). Methods: Using PRISMA guidelines, we reviewed randomized controlled trials (RCTs) published in 2010 or later that enrolled [less than or equal…
Descriptors: Randomized Controlled Trials, Interpersonal Competence, Sexuality, Health
Katherine Pye; Hannah Jackson; Teresa Iacono; Alan Shiell – Journal of Autism and Developmental Disorders, 2024
Many autistic children access some form of early intervention, but little is known about the value for money of different programs. We completed a scoping review of full economic evaluations of early interventions for autistic children and/or their families. We identified nine studies and reviewed their methods and quality. Most studies involved…
Descriptors: Economics, Early Intervention, Autism Spectrum Disorders, Children
Hsing-Chang Ni; Yi-Lung Chen; Hsiang-Yuan Lin – Journal of Autism and Developmental Disorders, 2025
Scarce clinical trials involving autistic people with intellectual disability (ID) and minimally speaking (MS) status have been a substantial unmet research need in the field. Although earlier studies have demonstrated the feasibility and beneficial potentials of repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal…
Descriptors: Autism Spectrum Disorders, Intellectual Disability, Youth, Verbal Ability
Yang, Yoon Jung; Chung, Kyong-Mee – Journal of Autism and Developmental Disorders, 2023
This study developed and tested the effectiveness of an app-based cognitive behavioral therapy (CBT) program in alleviating anxiety among adolescents and adults with autism without co-occurring intellectual disability. Thirty participants from 15 to 35 years old were randomly assigned to either the intervention or waitlist control group, and self-…
Descriptors: Pilot Projects, Randomized Controlled Trials, Handheld Devices, Behavior Modification
Victoria Grahame; Ashleigh Kernohan; Ehsan Kharati; Ayesha Mathias; Chrissie Butcher; Linda Dixon; Sue Fletcher-Watson; Deborah Garland; Magdalena Glod; Jane Goodwin; Saoirse Heron; Emma Honey; Ann Le Couteur; Leila Mackie; Jessica Maxwell; Lewis Montgomery; Emmanuel Ogundimu; Helen Probert; Deborah Riby; Priyanka Rob; Leanne Rogan; Laura Tavernor; Luke Vale; Elspeth Imogen Webb; Christopher Weetman; Jacqui Rodgers – Autism: The International Journal of Research and Practice, 2025
Restricted and repetitive behaviours vary greatly between autistic people. Some are a source of pleasure or create opportunities for learning; others may be detrimental in day-to-day life or cause harm. We have developed, in close collaboration with parents/carers, the Understanding Repetitive Behaviours programme, designed for families of young…
Descriptors: Repetition, Behavior Patterns, Cost Effectiveness, Randomized Controlled Trials
Laura Santos; Silvia Annunziata; Alice Geminiani; Alessia Ivani; Alice Giubergia; Daniela Garofalo; Arianna Caglio; Elena Brazzoli; Rossella Lipari; Maria Chiara Carrozza; Emilia Ambrosini; Ivana Olivieri; Alessandra Pedrocchi – Review Journal of Autism and Developmental Disorders, 2025
Robotic therapies are receiving growing interest in the autism field, especially for the improvement of social skills of children, enhancing traditional human interventions. In this work, we conduct a scoping review of the literature in robotics for autism, providing the largest review on this field from the last five years. Our work underlines…
Descriptors: Robotics, Autism Spectrum Disorders, Intervention, Program Effectiveness
Roberts, Megan Y.; Sone, Bailey J.; Jones, Maranda; Grauzer, Jeffrey; Sudec, Laura; Stern, Yael S.; Kwok, Elaine; Losh, Molly; Kaat, Aaron – Autism: The International Journal of Research and Practice, 2023
Coaching parents to use language facilitation strategies improves long-term language outcomes for autistic children. To optimize parent-mediated interventions, more studies need to explore factors that influence parents' learning. This study involved 119 autistic children (18-48 months) and their biological mothers enrolled in a single-site,…
Descriptors: Autism Spectrum Disorders, Parent Participation, Intervention, Randomized Controlled Trials
McDaniel, Jena; Brady, Nancy C.; Warren, Steven F. – Journal of Autism and Developmental Disorders, 2022
We conducted a systematic review to identify randomized controlled trials (RCTs) and single case research design (SCRD) studies of children with autism spectrum disorder that evaluate the effectiveness of responsivity intervention techniques for improving prelinguistic and/or language outcomes. Mean effect sizes were moderate and large for RCTs…
Descriptors: Outcomes of Treatment, Response to Intervention, Child Language, Autism Spectrum Disorders
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