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Experimental Evidence for a Child-to-Adolescent Switch in Human Amygdala-Prefrontal Cortex Communication: A Cross-Sectional Pilot Study

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Gee, Dylan G.; Hanson, Catherine; Caglar, Leyla Roksan; Fareri, Dominic S.; Gabard-Durnam, Laurel J.; Mills-Finnerty, Colleen; Goff, Bonnie; Caldera, Christina J.; Lumian, Daniel S.; Flannery, Jessica; Hanson, Stephen José; Tottenham, Nim – Developmental Science, 2022

Interactions between the amygdala and prefrontal cortex are fundamental to human emotion. Despite the central role of frontoamygdala communication in adult emotional learning and regulation, little is known about how top-down control emerges during human development. In the present cross-sectional pilot study, we experimentally manipulated…

Descriptors: Correlation, Diagnostic Tests, Brain Hemisphere Functions, Emotional Response