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Christian Röver; David Rindskopf; Tim Friede – Research Synthesis Methods, 2024
The trace plot is seldom used in meta-analysis, yet it is a very informative plot. In this article, we define and illustrate what the trace plot is, and discuss why it is important. The Bayesian version of the plot combines the posterior density of [tau], the between-study standard deviation, and the shrunken estimates of the study effects as a…
Descriptors: Graphs, Meta Analysis, Bayesian Statistics, Visualization
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Seitidis, Georgios; Tsokani, Sofia; Christogiannis, Christos; Kontouli, Katerina-Maria; Fyraridis, Alexandros; Nikolakopoulos, Stavros; Veroniki, Areti Angeliki; Mavridis, Dimitris – Research Synthesis Methods, 2023
Network meta-analysis (NMA) is an established method for assessing the comparative efficacy and safety of competing interventions. It is often the case that we deal with interventions that consist of multiple, possibly interacting, components. Examples of interventions' components include characteristics of the intervention, mode (face-to-face,…
Descriptors: Networks, Network Analysis, Meta Analysis, Intervention
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Konstantinos I. Bougioukas; Paschalis Karakasis; Konstantinos Pamporis; Emmanouil Bouras; Anna-Bettina Haidich – Research Synthesis Methods, 2024
Systematic reviews (SRs) have an important role in the healthcare decision-making practice. Assessing the overall confidence in the results of SRs using quality assessment tools, such as "A MeaSurement Tool to Assess Systematic Reviews 2" (AMSTAR 2), is crucial since not all SRs are conducted using the most rigorous methods. In this…
Descriptors: Programming Languages, Research Methodology, Decision Making, Medical Research
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Li, Hua; Shih, Ming-Chieh; Tu, Yu-Kang – Research Synthesis Methods, 2023
Component network meta-analysis (CNMA) compares treatments comprising multiple components and estimates the effects of individual components. For network meta-analysis, a standard network plot with nodes for treatments and edges for direct comparisons between treatments is drawn to visualize the evidence structure and the connections between…
Descriptors: Networks, Meta Analysis, Graphs, Comparative Analysis
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Turner, Simon Lee; Korevaar, Elizabeth; Cumpston, Miranda S.; Kanukula, Raju; Forbes, Andrew B.; McKenzie, Joanne E. – Research Synthesis Methods, 2023
Interrupted time series (ITS) studies are frequently used to examine the impact of population-level interventions or exposures. Systematic reviews with meta-analyses including ITS designs may inform public health and policy decision-making. Re-analysis of ITS may be required for inclusion in meta-analysis. While publications of ITS rarely provide…
Descriptors: Quasiexperimental Design, Graphs, Accuracy, Computation
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Belias, Michail; Rovers, Maroeska M.; Hoogland, Jeroen; Reitsma, Johannes B.; Debray, Thomas P. A.; IntHout, Joanna – Research Synthesis Methods, 2022
One of the main goals of an individual participant data meta-analysis (IPD-MA) of intervention studies is to investigate whether treatment effect differences are present, and how they are associated with patient characteristics. Examining treatment heterogeneity due to a continuous covariable (e.g., BMI or age) may be challenging, since there is…
Descriptors: Meta Analysis, Outcomes of Treatment, Prediction, Multivariate Analysis