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Hoffman, Janlyn R.; Brandwein, Nathan J.; Nguyen, Peter V. – Learning & Memory, 2019
Beta-adrenergic receptors ([beta]-ARs) prime hippocampal synapses to stabilize long-term potentiation (LTP). This "metaplasticity" can persist for 1-2 h after pharmacologic activation of [beta]-ARs. It requires activation of PKA (cAMP-dependent protein kinase) during [beta]-AR priming. A-kinase anchoring proteins (AKAPs) tether PKA to…
Descriptors: Animals, Science Experiments, Foreign Countries, Stimulation
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Huang, Guang-Zhe; Taniguchi, Mutsuo; Zhou, Ye-Bo; Zhang, Jing-Ji; Okutani, Fumino; Murata, Yoshihiro; Yamaguchi, Masahiro; Kaba, Hideto – Learning & Memory, 2018
The formation of mate recognition memory in mice is associated with neural changes at the reciprocal dendrodendritic synapses between glutamatergic mitral cell (MC) projection neurons and GABAergic granule cell (GC) interneurons in the accessory olfactory bulb (AOB). Although noradrenaline (NA) plays a critical role in the formation of the memory,…
Descriptors: Brain Hemisphere Functions, Biochemistry, Stimulation, Olfactory Perception