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Direct linkProvenzani, Umberto; Fusar-Poli, Laura; Brondino, Natascia; Damiani, Stefano; Vercesi, Marco; Meyer, Nicholas; Rocchetti, Matteo; Politi, Pierluigi – Autism: The International Journal of Research and Practice, 2020
The number of trials aimed at evaluating treatments for autism spectrum disorder has been increasing progressively. However, it is not clear which outcome measures should be used to assess their efficacy, especially for treatments which target core symptoms. The present review aimed to provide a comprehensive overview regarding the outcome…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Outcome Measures
Hardan, Antonio Y.; Hendren, Robert L.; Aman, Michael G.; Robb, Adelaide; Melmed, Raun D.; Andersen, Kristen A.; Luchini, Rachel; Rahman, Rezwanur; Ali, Sanjida; Jia, X Daniel; Mallick, Madhuja; Lateiner, Jordan E.; Palmer, Robert H.; Graham, Stephen M. – Autism: The International Journal of Research and Practice, 2019
Three phase 2 trials were conducted to assess the efficacy and long-term safety of weight-based memantine extended release (ER) treatment in children with autism spectrum disorder. MEM-MD-91, a 50-week open-label trial, identified memantine extended-release treatment responders for enrollment into MEM-MD-68, a 12-week randomized, double-blind,…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Drug Therapy
Download full textLopata, Christopher; Donnelly, James P.; Thomeer, Marcus L.; Rodgers, Jonathan D.; Lodi-Smith, Jennifer; Booth, Adam J.; Volker, Martin A. – Grantee Submission, 2020
A prior cluster randomized controlled trial (RCT) compared outcomes for a comprehensive school intervention (schoolMAX) to typical educational programming (services-as-usual [SAU]) for 103 children with autism spectrum disorder (ASD) without intellectual disability. The schoolMAX intervention was superior to SAU in improving social-cognitive…
Descriptors: Outcomes of Treatment, Intervention, Elementary School Students, Autism
