Data extraction is a crucial, yet labor-intensive and error-prone part of evidence synthesis. To date, efforts to harness machine learning for enhancing efficiency of the data extraction process have fallen short of achieving sufficient accuracy and usability. With the release of large language models (LLMs), new possibilities have emerged to…

Purpose: Multisite mediation studies are a cornerstone in mapping out developmental processes because they probe the mechanisms of a treatment while creating key opportunities to learn from and about variation in those mechanisms across sites. Despite the prevalence of multisite studies, a significant gap in the literature is how to plan such…

I. Purpose of the Study: Detecting whether interventions work or not (through main effect analysis) can provide empirical evidence regarding the causal linkage between malleable factors (e.g., interventions) and learner outcomes. In complement, moderation analyses help delineate for whom and under what conditions intervention effects are most…

Increasing concerns about the trustworthiness of research have prompted calls to scrutinise studies' Individual Participant Data (IPD), but guidance on how to do this was lacking. To address this, we developed the IPD Integrity Tool to screen randomised controlled trials (RCTs) for integrity issues. Development of the tool involved a literature…

Background: The emergence of causal research in education was almost strictly quantitative twenty years ago, however, that landscape has changed considerably. The number of intervention studies fielded and completed annually has increased substantially, and the quality of the evaluations is much more robust, including paying much greater attention…

Network meta-analysis (NMA) is an extension of pairwise meta-analysis (PMA) which combines evidence from trials on multiple treatments in connected networks. NMA delivers internally consistent estimates of relative treatment efficacy, needed for rational decision making. Over its first 20 years NMA's use has grown exponentially, with applications…

Some patients benefit from a treatment while others may do so less or do not benefit at all. We have previously developed a two-stage network meta-regression prediction model that synthesized randomized trials and evaluates how treatment effects vary across patient characteristics. In this article, we extended this model to combine different…

There is a considerable gap between many of the findings from educational psychology research and educational practice. This gap is especially notable in the field of science education. In this article, the implications of three categories of research and their findings for science educational policy in the USA and other jurisdictions were…

McKinney (2018) has argued that for the scholarship of teaching and learning (SoTL) to advance within a discipline, the integration of SoTL must be closely examined and opportunities for growth in SoTL must be recognized and discussed. To that end, this paper reflects on the degree to which SoTL is integrated into communication sciences and…

Randomised controlled trials of cancer treatments typically report progression free survival (PFS) and overall survival (OS) outcomes. Existing methods to synthesise evidence on PFS and OS either rely on the proportional hazards assumption or make parametric assumptions which may not capture the diverse survival curve shapes across studies and…

Rare events meta-analyses of randomized controlled trials (RCTs) are often underpowered because the outcomes are infrequent. Real-world evidence (RWE) from non-randomized studies may provide valuable complementary evidence about the effects of rare events, and there is growing interest in including such evidence in the decision-making process.…

The What Works Clearinghouse (WWC) identifies existing research on educational interventions, assesses the quality of the research, and summarizes and disseminates the evidence from studies that meet WWC standards. The WWC aims to provide enough information so educators can use the research to make informed decisions in their settings. This…

At every stage since the start of the pandemic, decisions across education and childcare have been informed by the scientific and medical evidence -- both on the risks of coronavirus (COVID-19) infection, transmission and illness, and on the known risks to children and young people not attending education settings -- balancing public health and…

This paper describes a 12-week cluster randomized controlled trial that examined the efficacy of BookNook, a virtual tutoring platform focused on reading. Cohorts of first- through fourth-grade students attending six Rocketship public charter schools in Northern California were randomly assigned within grades to receive BookNook. Intent-to-Treat…

This paper discusses, compares, and contrasts 4 different models for bringing evidence from randomised controlled trials (RCTs) into practice and into practical reasoning. I look at what questions the models can and cannot answer, what role they accord to RCT evidence, and what their possible attraction for practitioners might be. The models are…