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Sawhney, Indermeet; Zia, Asif; Adams, Danielle; Gates, Bob – British Journal of Learning Disabilities, 2019
Background: It is well established that valproate, and its valproic acid, sodium valproate, and valproate semisodium forms is a highly teratogenic drug and evidence suggests that use in pregnancy leads to physical birth defects in 10% of children born compared with a background rate of 2% to 3%. Congenital malformations associated with valproate…
Descriptors: Females, Intellectual Disability, At Risk Persons, Pregnancy
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Lucas, Marcella M.; Lenck-Santini, Pierre-Pascal; Holmes, Gregory L.; Scott, Rod C. – Brain, 2011
One of the most common and serious co-morbidities in patients with epilepsy is cognitive impairment. While early-life seizures are considered a major cause for cognitive impairment, it is not known whether it is the seizures, the underlying neurological substrate or a combination that has the largest impact on eventual learning and memory. Teasing…
Descriptors: Animals, Epilepsy, Mental Retardation, Seizures
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van der Heide, D. C.; van der Putten, A. A. J.; van den Berg, P. B.; Taxis, K.; Vlaskamp, C. – Journal of Intellectual Disability Research, 2009
Background: Persons with profound intellectual and multiple disabilities (PIMD) suffer from a wide range of health problems and use a wide range of different drugs. This study investigated for frequently used medication whether there was a health problem documented in the medical notes for the drug prescribed. Method: Persons with PIMD with an…
Descriptors: Drug Use, Severe Mental Retardation, Physical Health, Residential Institutions
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Titze, Karl; Koch, Sabine; Helge, Hans; Lehmkuhl, Ulrike; Rauh, Hellgard; Steinhausen, Hans-Christoph – Developmental Medicine & Child Neurology, 2008
The offspring of mothers with epilepsy are considered to be at developmental risk during pregnancy from: (1) generalized maternal seizures (hypoxia); (2) teratogenicity of antiepileptic drugs (AEDs); and (3) adverse socio-familial conditions associated with having a chronically sick mother. Sixty-seven children of mothers with epilepsy and 49…
Descriptors: Mothers, Epilepsy, Seizures, Pregnancy
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Joe, Sean; Joe, Emanique; Rowley, Larry L. – Review of Research in Education, 2009
Educational research, practice, and institutions regularly highlight the significance of factors outside of schooling that affect children's engagement and participation in classroom learning. The health of children and families is one such issue with implications for the quality of children's school experiences, treatment in school, and academic…
Descriptors: Educational Research, Elementary Secondary Education, Mental Disorders, Academic Achievement
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Yen, Chia-Feng; Lin, Jin-Ding; Loh, Ching-Hui; Shi, Leiyu; Hsu, Shang-Wei – Research in Developmental Disabilities: A Multidisciplinary Journal, 2009
Direct family caregivers of population-based adolescents with intellectual disabilities in Taiwan were surveyed regarding their perceptions of the use of prescribed medication and its relationship with health-related behaviors, medical care and preventive health utilization of people with intellectual disabilities. Cross-sectional data on 1419…
Descriptors: Attitude Measures, Drug Therapy, Health Behavior, Prevention