This is the second volume in a two volume set covering research conducted as part of the Monitoring the Future study of young adults. It presents the results of the 1977 through 2000 follow-up surveys of the graduating high school classes of 1976 through 1999 as these respondents have progressed into adulthood. In order for this volume to stand alone, some material has been repeated from volume 1. Specifically, chapter 2 is repeated from volume 1, and provides an overview of the key findings. Chapter 3, on study design and procedures, is also repeated. Chapter 4 examines the prevalence of drug use in early and middle adulthood, and chapter 5 presents trends in drug use. Chapter 6 presents their attitudes and beliefs about drugs, while Chapter 7 discusses the social milieu. Chapters 8 and 9 look at the prevalence and trends in drug use among college students. (Contains 30 tables and 73 figures.) (JDM)