Objectives: To investigate the psychometric properties of the BMSLSS-College among 723 college students. Methods: Internal consistency estimates explored scale reliability, factor analysis explored construct validity, and known-groups validity was assessed using the National College Youth Risk Behavior Survey and Harvard School of Public Health College Alcohol Study. Criterion-related validity was explored through analyses with the CDC's health-related quality of life scale and a social isolation scale. Results: Acceptable internal consistency reliability, construct, known-groups, and criterion-related validity were established. Conclusions: Findings offer preliminary support for the BMSLSS-C; it could be useful in large-scale research studies, applied screening contexts, and for program evaluation purposes toward achieving Healthy People 2010 objectives.