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Hyporesponsive Reward Anticipation in the Basal Ganglia following Severe Institutional Deprivation Early in Life
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Mehta, Mitul A.; Gore-Langton, Emma; Golembo, Nicole; Colvert, Emma; Williams, Steven C. R.; Sonuga-Barke, Edmund – Journal of Cognitive Neuroscience, 2010
Severe deprivation in the first few years of life is associated with multiple difficulties in cognition and behavior. However, the brain basis for these difficulties is poorly understood. Structural and functional neuroimaging studies have implicated limbic system structures as dysfunctional, and one functional imaging study in a heterogeneous…
Descriptors: Etiology, Foreign Countries, Brain, Rewards
Amygdala, Hippocampal and Corpus Callosum Size Following Severe Early Institutional Deprivation: The English and Romanian Adoptees Study Pilot
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Mehta, Mitul A.; Golembo, Nicole I.; Nosarti, Chiara; Colvert, Emma; Mota, Ashley; Williams, Steven C. R.; Rutter, Michael; Sonuga-Barke, Edmund J. S. – Journal of Child Psychology and Psychiatry, 2009
The adoption into the UK of children who have been reared in severely deprived conditions provides an opportunity to study possible association between very early negative experiences and subsequent brain development. This cross-sectional study was a pilot for a planned larger study quantifying the effects of early deprivation on later brain…
Descriptors: Disadvantaged, Foreign Countries, Brain, Cognitive Processes
Normality and Impairment following Profound Early Institutional Deprivation: A Longitudinal follow-up into Early Adolescence
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Kreppner, Jana M.; Rutter, Michael; Beckett, Celia; Castle, Jenny; Colvert, Emma; Groothues, Christine; Hawkins, Amanda; O'Connor, Thomas G.; Stevens, Suzanne; Sonuga-Barke, Edmund J. S. – Developmental Psychology, 2007
Longitudinal analyses on normal versus impaired functioning across 7 domains were conducted in children who had experienced profound institutional deprivation up to the age of 42 months and were adopted from Romania into U.K. families. Comparisons were made with noninstitutionalized children adopted from Romania and with nondeprived within-U.K.…
Descriptors: Foreign Countries, Disadvantaged Environment, Early Adolescents, Brain