Self-efficacy is an important cognitive predictor of substance abuse treatment outcome. Although measures of coping self-efficacy are related to substance use relapse in adults, their properties are not well-known in adolescent populations. The present study examined 223 adolescents while in treatment for substance abuse and comorbid psychiatric disorders. Responses on the Drug-Taking Confidence Questionnaire (DTCQ; Sklar, Annis, & Turner, 1997) were used to construct a 37-item, 5-factor version for use with adolescents. Exploratory and confirmatory factor analysis identified the following factors: (1) negative situations, (2) social/drugs,(3) pleasant emotions, (4) testing personal control, and (5) physical/intimate. Data preliminarily support the construct, concurrent, and predictive validity of the revised instrument. (Contains 4 tables and 1 figure.)