Over the past decade, mechanistic cross-linking probes have been used to study protein-protein interactions in natural product biosynthetic pathways. This approach is highly interdisciplinary, combining elements of protein biochemistry, organic chemistry, and computational docking. Herein, we described the development of an experiment to engage…

A simple setup is designed to investigate a "time-of-flight" measurement of the speed of sound in water. This experiment only requires low cost components and is also very simple to understand by students. It could be easily used as a demonstration experiment.

A number of organisations have provided instructions on how to produce small quantities of liquid oxygen in the classroom using liquid nitrogen and a copper condensation coil (Lister 1995 "Classic Chemistry Demonstrations" (London: Royal Society of Chemistry) pp 61-2, French and Hibbert 2010 "Phys. Educ." 45 221-2). The method…

The blue bottle experiment is a popular chemical demonstration because of its simplicity and visual appeal. Most papers on the topic focus on a new formulation or a new presentation, but only a few discuss pedagogical application for a full lab session. This article describes the use of this experiment in the first session of undergraduate…

Rania Gikopoulou is a primary school teacher and post-doctoral researcher at the National and Kapodistrian University of Athens. In this article she describes how her 5th grade class (Age 11) learned about abstract phenomena through models of their microscopic structure.

In this exercise, an actual chemical reaction, oxidation of iron in air, is studied along with a related analogue simulation of that reaction. The rusting of steel wool is carried out as a class effort. The parallel simulation is performed by students working in small groups. The analogue for the reacting gas is a countable set of discrete marble…

A vectorial representation of the full sequence of events occurring during the 2D-NMR heteronuclear single-quantum correlation (HSQC) experiment is presented. The proposed vectorial representation conveys an understanding of the magnetization evolution during the HSQC pulse sequence for those who have little or no quantum mechanical background.…

A laboratory experiment is described in which a simple characterization of a historical lime mortar is made by the determination of its approximate composition by a gravimetric method. Fourier transform infrared (FTIR) spectroscopy and X-ray diffraction (XRD) are also used for the qualitative characterization of the lime mortar components. These…

There is an increasing focus across all educational sectors to ensure that learning objectives are aligned with learning activities and assessments. An attractive approach previously published is that of curriculum alignment projects. This paper discusses the use of the fun and famous "Elephant's Toothpaste" experiment as a customizable…

The Ruben Flame Tube is named after H. Ruben, who published the demonstration experiment in "Annalen der Physik" in 1905. This article presents one of the many demonstrations the author uses to engage, motivate, and challenge his students.

A Smartphone is not only a mobile device that is used for communication but is also integrated with a personal digital assistant (PDA) and other technological capabilities such as built-in acceleration, magnetic and light sensors, microphone, camera and Global Positioning System (GPS) unit. This handheld device has become very popular with the…

Guided-inquiry lab activities with bean beetles ("Callosobruchus maculatus") teach students how to develop hypotheses, design experiments, identify experimental variables, collect and interpret data, and formulate conclusions. These activities provide students with real hands-on experiences and skills that reinforce their understanding of the…

This article introduces students to the world of digital microscopy. Looking at small objects through a digital microscope is like traveling through a foreign country for the first time. The experience is new, engaging, and exciting. A handheld digital microscope is an essential tool in a 21st century teacher's toolkit and the perfect tool to…

In the fall of 2011, Park Forest Middle School (PFMS) students approached the STEM faculty with numerous questions regarding the popular television show Myth Busters, which detailed Greek mathematician, physicist, engineer, and inventor, Archimedes. Two episodes featured attempts to test historical accounts that Archimedes developed a death ray…

The scientific method is arguably the most reliable way to understand the physical world, yet this aspect of science is rarely addressed in introductory science courses. Students typically learn about the theory in its final, refined form, and seldom experience the experiment-to-theory cycle that goes into producing the theory. One exception to…