Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

Mass spectrometry is essential for large-scale protein identification in proteomics. By database searching of mass spectrometry data, it is possible to identify proteins without the need to interpret MS/MS spectra (de novo sequencing), which is time-consuming and not feasible as a systematic tool in proteomic analysis. Many authors have reported…

Within the eukaryotic cell, the actin cytoskeleton is a crucial structural framework that maintains cellular form, regulates cell movement and division, and facilitates the internal transportation of proteins and organelles. External cues induce alterations in the actin cytoskeleton primarily through the activation of Rho GTPases, which then bind…

Analyzing and interpreting data is essential to the practice of scientists and is also an essential science and engineering practice for science teaching and learning. Although working with data has benefits for student learning, it is also challenging, particularly with respect to aspects of work with data that are not yet very common in schools,…

To fully appreciate genetics, one must understand the link between genotype (DNA sequence) and phenotype (observable characteristics). Advances in high-throughput genomic sequencing technologies and applications, so-called "-omics," have made genetic sequencing readily available across fields in biology from applications in…

Many introductory astronomy courses include concepts related to basic stellar properties. In general, these are concepts that originate from the human perception of starlight. This observational aspect is not easy to incorporate in the classroom. We explore if these concepts could be developed using the built-in data in a planetarium software.…

This essential science methods resource integrates principles of learning and motivation with practical teaching ideas for the elementary and middle school science classroom. It employs project-based learning (PBL) to enable educators to engage their students in meaningful, real-world questioning about the world. It provides concrete strategies…

To learn with data, students need "data" to explore. This can be deceptive--data-rich experiences typically involve much more than a straightforward science lab. Solving real problems with data means identifying authentic questions that are meaningful to students and provide a foundation for deep inquiry. Such situations often lend…

Nitrogen- or phosphorus-based fertilizers, used in agriculture, can run off into nearby waterways during periods of heavy rain or high flow and cause harmful blooms (Paerl et al. 2016), low oxygen (Joyce 2000), and decreased biodiversity (Sebens 1994). Studies of the effects wetlands can have on water and habitat quality (Verhoeven and Meuleman…

Advances in 3D printing technology over the past decade have led to its expansion into all subfields of science, including chemistry. This technology provides useful teaching tools that facilitate communication of difficult chemical concepts to students and researchers. Presented here is the use of 3D printing technology to create tangible models…

This article is aimed at teachers already experienced with activities involving small, student-collected data sets and who are now ready to begin working with large, online data sets collected by scientists and engineers. The authors discuss challenges, instructional strategies, and sources of appropriate lesson plans. With guidance, plus online…

Renee Clary and James Wandersee implemented the Stratigraphy and Data Interpretation Project described in this article when they recognized that some students were having difficulties constructing appropriate graphics and interpreting their constructed graphics for an earlier mathematics-science project in their classrooms. They also previously…

Many students enter high school with some science knowledge and experience doing investigations but often know little about the nature of science (NOS) or how the knowledge is developed (i.e., science practices). As science teachers, we need to get students excited about science as quickly as possible with activities that introduce the practices…

Data literacy is complex. When students investigate the natural world, they must be able to gather data, organize it in tables and spreadsheets, analyze it in context, and describe and interpret it--usually as evidence to support a scientific argument. These skills are echoed in the science and engineering practices of the "Next Generation…

Analyzing evolutionary relationships requires that students have a thorough understanding of evidence and of how scientists use evidence to develop these relationships. In this lesson sequence, students work in groups to process many different lines of evidence of evolutionary relationships between ungulates, then construct a scientific argument…