This essential science methods resource integrates principles of learning and motivation with practical teaching ideas for the elementary and middle school science classroom. It employs project-based learning (PBL) to enable educators to engage their students in meaningful, real-world questioning about the world. It provides concrete strategies…

Analyzing and interpreting data is essential to the practice of scientists and is also an essential science and engineering practice for science teaching and learning. Although working with data has benefits for student learning, it is also challenging, particularly with respect to aspects of work with data that are not yet very common in schools,…

Biochemistry is a data-heavy discipline, yet teaching students to work with large datasets is absent from many undergraduate Biochemistry programs. Ensuring that future generations of students are confident in tackling problems using big data first requires that educators become comfortable teaching big data skills. The activity described herein…

Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

School science is often very different from "real world" science. One important difference, and possibly the main one, is that in school science the relationships between variables have often been sanitized -- essentially "cleaned up" -- so that there is very little (and often no) variation in the data from the relationship…

Classroom observation data using tools such as the Classroom Observation Protocol for Undergraduate STEM (COPUS) are frequently collected in instructional settings for large-scale research studies and program assessment. While COPUS data may be provided to instructors, it is often provided with little or no guidance on how the data can be used to…

Mass spectrometry is essential for large-scale protein identification in proteomics. By database searching of mass spectrometry data, it is possible to identify proteins without the need to interpret MS/MS spectra (de novo sequencing), which is time-consuming and not feasible as a systematic tool in proteomic analysis. Many authors have reported…

Within the eukaryotic cell, the actin cytoskeleton is a crucial structural framework that maintains cellular form, regulates cell movement and division, and facilitates the internal transportation of proteins and organelles. External cues induce alterations in the actin cytoskeleton primarily through the activation of Rho GTPases, which then bind…

Nitrogen- or phosphorus-based fertilizers, used in agriculture, can run off into nearby waterways during periods of heavy rain or high flow and cause harmful blooms (Paerl et al. 2016), low oxygen (Joyce 2000), and decreased biodiversity (Sebens 1994). Studies of the effects wetlands can have on water and habitat quality (Verhoeven and Meuleman…

Citizen science is a research collaboration between scientists and volunteers who provide data for education, conservation, and environmental protection. Volunteers, often the locals in the area, provide data on species occurrence while researchers perform distribution mapping or other data analysis. Social networking sites including Facebook,…

To fully appreciate genetics, one must understand the link between genotype (DNA sequence) and phenotype (observable characteristics). Advances in high-throughput genomic sequencing technologies and applications, so-called "-omics," have made genetic sequencing readily available across fields in biology from applications in…

Many introductory astronomy courses include concepts related to basic stellar properties. In general, these are concepts that originate from the human perception of starlight. This observational aspect is not easy to incorporate in the classroom. We explore if these concepts could be developed using the built-in data in a planetarium software.…

This article provides two activities, exploring genetic drift of small breeding populations, highlighting the black-footed ferret ("Mustela nigripes"). According to the U.S. Fish and Wildlife service, all black-footed ferrets are descended from 18 individuals, making them extremely vulnerable to genetic drift. They were thought to be…

Understanding how scientific conclusions are drawn from data is central to learning about the nature of science. Many students struggle with aspects of reasoning from data, including identifying relationships among variables, interpreting graphs, coordinating theory and evidence, and not allowing personal beliefs to outweigh the data when forming…

A multiweek laboratory experiment is described, which guides students to use data to make decisions through multiple steps, before reaching a final conclusion. The lab focuses on the comparisons of fluorescence and absorbance spectroscopies to determine the concentration of a desired substance in an unknown sample in consideration of a complex…