Double blind study compared effects of two drug treatments, naloxone hydrochloride and naltrexone hydrochloride, on self-injurious behavior of a 12-year-old mentally retarded and autistic girl. Self-injury increased with naloxone treatment but decreased to near zero with naltrexone, a change which persisted at follow-up 22 months after treatment.…

Assessment of self-injurious behavior (SIB) in three individuals with developmental disabilities revealed that the behavior was an escape response maintained by negative reinforcement. Treatment consisted of extinction plus instructional fading and resulted in immediate and large reductions in SIB behaviors. Maintenance occurred as instruction…

This study effectively eliminated face-slapping behavior in a 10-year-old boy with severe developmental disability and autistic characteristics. The subject wore wrist weights for up to 30 minutes each day. Face slapping did not occur during a follow-up check conducted five months after study completion. (Author/DB)