This publication is a response to problems encountered with substance abuse curricula. It represents the best current thinking about drug prevention education. It shows what to look for when adopting or adapting ready-made curricula, and suggests important lessons that ought to be part of any prevention-education sequence, including those developed by schools and school systems for their own use. The document opens with a summary checklist of the essential points to consider in selecting a prevention curriculum, adapting one for one's special needs, or designing one's own. This checklist is divided into three parts: before one begin, as one chooses a curriculum, and when the curriculum is implemented. These points are among those listed: (1) determine the nature and extent of the drug problem in one's area; (2) develop a clear, concise policy against drug use in one's school; (3) commit to using a curriuculum that conveys the no-use message; (4) provide for keeping parents informed about the curriculum; (5) establish a schedule for implementation and monitoring; (6) provide regular assessment; and (7) maintain communication among all persons and groups involved in the drug prevention efforts. Curriculum guidelines are given for early childhood, upper elementary, middle school and junior high school, and high school levels. The appendices include lists of Department of Education resources, other federal activities, and state agencies. (ABL)