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Direct linkLord, Catherine; McCauley, James B.; Pepa, Lauren A.; Huerta, Marisela; Pickles, Andrew – Autism: The International Journal of Research and Practice, 2020
Longitudinal data on the functioning of adults referred for possible autism as children are sparse and possibly different from datasets consisting of adult clinical referrals. A total of 123 young adults, mean age of 26, referred for neurodevelopmental disorders in early childhood were categorized into three outcome groups: autism spectrum…
Descriptors: Autism, Pervasive Developmental Disorders, Young Adults, Intelligence Quotient
Lewis, Alan S.; van Schalkwyk, Gerrit Ian; Lopez, Mayra Ortiz; Volkmar, Fred R.; Picciotto, Marina R.; Sukhodolsky, Denis G. – Journal of Autism and Developmental Disorders, 2018
Nicotinic acetylcholine receptors (nAChRs), particularly the a7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight…
Descriptors: Aggression, Adults, Stimulants, Pervasive Developmental Disorders
Beasley, Joan B.; Kalb, Luther; Klein, Ann – Journal of Mental Health Research in Intellectual Disabilities, 2018
Individuals with intellectual disability (ID) experience high rates of psychiatric disorders, and coinciding high rates of emergency service use. The current study seeks to explore strategies to improve outcomes by reporting a one-year prospective investigation among 41 individuals (Mean age = 32 years, SD = 12) with ID and mental health needs who…
Descriptors: Intellectual Disability, Rural Areas, Mental Disorders, Comorbidity
Mazurek, Micah O.; Lu, Frances; Macklin, Eric A.; Handen, Benjamin L. – Autism: The International Journal of Research and Practice, 2019
The newest edition of the "Diagnostic and Statistical Manual of Mental Disorders" (5th ed., DSM-5) introduced substantial changes to the diagnostic criteria for autism spectrum disorder, including new severity level ratings for social communication and restricted and repetitive behavior domains. The purpose of this study was to evaluate…
Descriptors: Severity (of Disability), Autism, Pervasive Developmental Disorders, Clinical Diagnosis
Scahill, Lawrence; Aman, Michael G.; Lecavalier, Luc; Halladay, Alycia K.; Bishop, Somer L.; Bodfish, James W.; Grondhuis, Sabrina; Jones, Nancy; Horrigan, Joseph P.; Cook, Edwin H.; Handen, Benjamin L.; King, Bryan H.; Pearson, Deborah A.; McCracken, James T.; Sullivan, Katherine Anne; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2015
Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized…
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Problems, Repetition
Download full textLocke, Jill; Hugh, Maria L.; Pullmann, Michael D.; Cook, Heather; Coifman, Jessica; McRee, Erin; Joshi, Mahima; Lyon, Aaron R.; Schwartz, Ilene – Grantee Submission, 2021
The increased prevalence of autism in the United States (1 in 54 youth) requires educators to implement evidence-based practices (EBPs). However, it is unclear which EBPs, if any, general and special education teachers and paraeducators are commonly trained to use or whether they consistently use those EBPs to support the inclusion of students…
Descriptors: Autism, Pervasive Developmental Disorders, Evidence Based Practice, Special Education Teachers
Sannar, Elise M.; Palka, Tamara; Beresford, Carol; Peura, Christine; Kaplan, Desmond; Verdi, Mary; Siegel, Matthew; Kaplan, Shir; Grados, Marco – Journal of Autism and Developmental Disorders, 2018
We examined the relationship between sleep duration and awakenings to Aberrant Behavior Checklist-Community (ABC-C) and Autism Diagnostic Observation Schedule (ADOS-2) scores in hospitalized youth with ASD and behavioral disturbance. Participants included 106 patients with a stay of at least 10 nights. Sleep in the hospital was recorded by staff…
Descriptors: Sleep, Correlation, Behavior Problems, Severity (of Disability)
Fung, Lawrence K.; Libove, Robin A.; Phillips, Jennifer; Haddad, Francois; Hardan, Antonio Y. – Journal of Autism and Developmental Disorders, 2014
The objective of this study was to assess the tolerability and efficacy of pregnenolone in reducing irritability in adults with autism spectrum disorder (ASD). This was a pilot, open-label, 12-week trial that included twelve subjects with a mean age of 22.5 ± 5.8 years. Two participants dropped out of the study due to reasons unrelated to adverse…
Descriptors: Adults, Pervasive Developmental Disorders, Autism, Drug Therapy
Sabine S. Chebli; Valérie Martin; Marc J. Lanovaz – Review Journal of Autism and Developmental Disorders, 2016
Although many researchers have examined the prevalence of stereotypy in individuals with developmental disabilities, the results of previous studies have not been aggregated and analyzed methodically. Thus, we conducted a systematic review of studies reporting the prevalence of stereotypy in individuals with developmental disabilities. Our results…
Descriptors: Autism Spectrum Disorders, Behavior Problems, Incidence, Developmental Disabilities
Walton, Catherine; Kerr, Mike – Journal of Applied Research in Intellectual Disabilities, 2016
Background: The diagnosis of depression in severe and profound intellectual disability is challenging. Without adequate skills in verbal self-expression, standardized diagnostic criteria cannot be used with confidence. The purpose of this systematic review was to investigate the assessment and diagnosis of unipolar depression in severe and…
Descriptors: Severe Intellectual Disability, Incidence, Depression (Psychology), Clinical Diagnosis
Erickson, Craig A.; Wink, Logan K.; Early, Maureen C.; Stiegelmeyer, Elizabeth; Mathieu-Frasier, Lauren; Patrick, Vanessa; McDougle, Christopher J. – Journal of Autism and Developmental Disorders, 2014
Rationale: An excitatory/inhibitory (E:I) imbalance marked by enhanced glutamate and deficient gamma-aminobutyric acid (GABA) neurotransmission may contribute to the pathophysiology of autism spectrum disorders (ASD). Objectives: We report on the first single-blind placebo lead-in trial of acamprosate, a drug with putative mechanisms restoring E:I…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Metabolism
Siegel, Matthew; Milligan, Briana; Stein, Hannah; Teer, Olivia; Smith, Kahsi A. – Journal of Intellectual Disabilities, 2013
To advance clinical care and research in children with intellectual disability and autism there is a growing need for efficient means to measure behavioral severity and response to treatment. The objective of this study was to assess the feasibility of telephone administration of the Aberrant Behavior Checklist-Irritability Subscale (ABC-I). The…
Descriptors: Telephone Surveys, Antisocial Behavior, Check Lists, Feasibility Studies
Barnes, Madalyn; Bernau, Megan; Johnson, Lindsay; Melchert, Jordin; Patek, Madeline; Zebrowski, Kaeleigh; Moser, Christy Szczech – Journal of Occupational Therapy, Schools & Early Intervention, 2019
Numerous research studies have been completed on the topic of Autism Spectrum Disorder (ASD). As individuals with this diagnosis are frequently treated by occupational therapists, this review will focus on research that has been completed on ASD that will provide insights into the understanding and treatment of children on the spectrum.
Descriptors: Autism, Pervasive Developmental Disorders, Occupational Therapy, Allied Health Personnel
Scahill, Lawrence; Hallett, Victoria; Aman, Michael G.; McDougle, Christopher J.; Arnold, L. Eugene; McCracken, James T.; Tierney, Elaine; Deng, Yanhong; Dziura, James; Vitiello, Benedetto – Journal of Autism and Developmental Disorders, 2013
There is growing interest in measuring social disability as a core element of autism spectrum disorders in medication trials. We conducted a secondary analysis on the Aberrant Behavior Checklist Social Withdrawal subscale using data from two federally-funded, multi-site, randomized trials with risperidone. Study 1 included 52 subjects assigned to…
Descriptors: Autism, Pharmacology, Effect Size, Pervasive Developmental Disorders
Bearss, Karen; Johnson, Cynthia; Handen, Benjamin; Smith, Tristram; Scahill, Lawrence – Journal of Autism and Developmental Disorders, 2013
Guidance on effective interventions for disruptive behavior in young children with autism spectrum disorders (ASDs) is limited. We present feasibility and initial efficacy data on a structured parent training program for 16 children (ages 3-6) with ASD and disruptive behavior. The 6-month intervention included 11 Core and up to 2 Optional…
Descriptors: Parents, Autism, Young Children, Parent Education
