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Concomitant Medication Use in Children with Autism Spectrum Disorder: Data from the Autism Biomarkers Consortium for Clinical Trials
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Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Gastrointestinal Problems Are Associated with Increased Repetitive Behaviors but Not Social Communication Difficulties in Young Children with Autism Spectrum Disorders
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Chakraborty, Payal; Carpenter, Kimberly L. H.; Major, Samantha; Deaver, Megan; Vermeer, Saritha; Herold, Brianna; Franz, Lauren; Howard, Jill; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2021
Individuals with autism spectrum disorder are more likely than typically developing individuals to experience a range of gastrointestinal abnormalities, including chronic diarrhea, constipation, food sensitivities, and abdominal pain. These gastrointestinal symptoms have been associated with higher levels of irritability and aggressive behavior,…
Descriptors: Autism, Pervasive Developmental Disorders, Human Body, At Risk Persons
Individual Temperament and Problem Behavior in Children with Autism Spectrum Disorders
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Adamek, Lauren; Nichols, Shana; Tetenbaum, Samara P.; Bregman, Joel; Ponzio, Christine A.; Carr, Edward G. – Focus on Autism and Other Developmental Disabilities, 2011
Temperament is important for considering differences among diagnostic groups and for understanding individual differences that predict problematic behavior. Temperament characteristics, such as negative affectivity, effortful control, and surgency (highly active and impulsive), are predictive of externalizing behavior in typically developing…
Descriptors: Autism, Personality Traits, Individual Differences, Pervasive Developmental Disorders