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Direct linkWoodard, Cooper; Groden, June; Goodwin, Matthew; Bodfish, James – Autism: The International Journal of Research & Practice, 2007
We used a mixed group/single-case, double-blind, placebo-controlled, ABAB design to examine the safety and efficacy of the glutamate antagonist dextromethorphan for the treatment of problematic behaviors and core symptoms in eight children diagnosed with autism. All participants had increased levels of irritability at baseline as measured by the…
Descriptors: Drug Therapy, Behavior Problems, Symptoms (Individual Disorders), Children
