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Direct linkHirota, Tomoya; Deserno, Marie; McElroy, Eoin – Journal of Autism and Developmental Disorders, 2020
Irritability and aggression (IA) are highly prevalent in individuals with autism spectrum disorder (ASD). Although clinical correlates of IA in this population have been previously examined, findings from existing studies capturing symptoms as a set of latent variables do not fully explain meaningful associations between the symptoms themselves.…
Descriptors: Aggression, Antisocial Behavior, Autism, Pervasive Developmental Disorders
Chez, Michael; Kile, Shawn; Lepage, Christopher; Parise, Carol; Benabides, Bobbie; Hankins, Andrea – Journal of Autism and Developmental Disorders, 2020
Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…
Descriptors: Outcomes of Treatment, Randomized Controlled Trials, Pilot Projects, Drug Therapy
Dean, Olivia M.; Gray, Kylie; Dodd, Seetal; Villagonzalo, Kristi-Ann; Brown, Ellie; Tonge, Bruce; Berk, Michael; Byrne, Linda K. – Journal of Intellectual & Developmental Disability, 2019
Background: Traditional treatment for the behavioural symptoms in autism spectrum disorder (ASD) remains unsatisfactory. There is an urgent need for new, biologically relevant therapies that target both the core and comorbid symptoms that children may experience. This article builds on research previously published by the authors. Method: We…
Descriptors: Autism, Pervasive Developmental Disorders, Intervention, Children
Lewis, Alan S.; van Schalkwyk, Gerrit Ian; Lopez, Mayra Ortiz; Volkmar, Fred R.; Picciotto, Marina R.; Sukhodolsky, Denis G. – Journal of Autism and Developmental Disorders, 2018
Nicotinic acetylcholine receptors (nAChRs), particularly the a7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight…
Descriptors: Aggression, Adults, Stimulants, Pervasive Developmental Disorders
Merineau-Cote, J.; Morin, D. – Journal of Intellectual Disability Research, 2013
Background: Some individuals with intellectual disabilities (IDs) exhibit aggressive behaviour directed towards themselves, others or the environment. Displaying aggressive behaviour is associated with a number of negative consequences such as the exposure to restrictive interventions. This study aims to identify personal and environmental factors…
Descriptors: Mental Retardation, Adults, Aggression, Behavior Problems
Rojahn, J.; Rowe, E. W.; Sharber, A. C.; Hastings, R.; Matson, J. L.; Didden, R.; Kroes, D. B. H.; Dumont, E. L. M. – Journal of Intellectual Disability Research, 2012
Background: The Behavior Problems Inventory-01 (BPI-01) is an informant-based behaviour rating instrument for intellectual disabilities (ID) with 49 items and three sub-scales: "Self-injurious Behavior," "Stereotyped Behavior" and "Aggressive/Destructive Behavior." The Behavior Problems Inventory-Short Form (BPI-S) is…
Descriptors: Behavior Problems, Severe Disabilities, Self Destructive Behavior, Mental Retardation
Dunlap, Glen; Carr, Edward G.; Horner, Robert H.; Koegel, Robert L.; Sailor, Wayne; Clarke, Shelley; Koegel, Lynn Kern; Albin, Richard W.; Vaughn, Bobbie J.; McLaughlin, Darlene Magito; James, Kim Mullen; Todd, Anne W.; Newton, J. Stephen; Lucyshyn, Joseph; Griggs, Peter; Bohanon, Hank; Choi, Jeong Hoon; Vismara, Laurie; Minjarez, Mendy Boettcher; Buschbacher, Pamelazita; Fox, Lise – Behavioral Disorders, 2010
A major goal of positive behavior support (PBS) is to produce broad-based, long-term improvements in adaptive behavior; however, the empirical base, at present, is mainly composed of relatively short-term studies carried out in circumscribed contexts. Therefore, a need exists for reliable data that can inform the field regarding the comprehensive…
Descriptors: Intervention, Quality of Life, Behavior Modification, Rating Scales
Myrbakk, Even; Von Tetzchner, Stephen – Journal of Mental Health Research in Intellectual Disabilities, 2008
With the desegregation processes of services for people with intellectual disability (ID) that is taking place in most Western countries there is a need for more knowledge related to the prevalence of behavior problems among people living in community settings. This study investigates the prevalence of behavior problems among 140 adolescents and…
Descriptors: Municipalities, Behavior Problems, Incidence, Autism
Peer reviewedRojahn, Johannes; Aman, Michael G.; Matson, Johnny L.; Mayville, Erik – Research in Developmental Disabilities, 2003
A study compared the Aberrant Behavior Checklist (ABC) and the Behavior Problems Inventory (BPI) for assessing the maladaptive behavior of 226 adults, mostly with severe or profound mental retardation. Individuals with elevated BPI scores generally had higher ABC scores, however, the extent of covariation differed across subscales. (Contains…
Descriptors: Adult Education, Adults, Aggression, Behavior Problems
