The guide presents concepts and approaches to prevention of alcohol and other drug (AOD) abuse among college students, focusing on the role of faculty in prevention efforts. Sections discuss why faculty should get involved, the impact of AOD abuse on academic performance, the rationale for taking an environmental approach to prevention, helping students who are experiencing problems, motivating faculty interest in prevention, ways in which academic departments can support prevention, active learning opportunities through service learning, and using academics to generate student involvement in prevention efforts. Lists of publications, organizations, and relevant World Wide Web sites that can be used as further resources are appended. (MSE)