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Direct linkSantos, Ana Rita; Kanellopoulos, Alexandros K.; Bagni, Claudia – Learning & Memory, 2014
The Fragile X syndrome (FXS) is the most frequent form of inherited mental disability and is considered a monogenic cause of autism spectrum disorder. FXS is caused by a triplet expansion that inhibits the expression of the "FMR1" gene. The gene product, the Fragile X Mental Retardation Protein (FMRP), regulates mRNA metabolism in brain…
Descriptors: Genetic Disorders, Mental Retardation, Pervasive Developmental Disorders, Autism
