Fully-Latent Principal Stratification (FLPS) offers a promising approach for estimating treatment effect heterogeneity based on patterns of students' interactions with Intelligent Tutoring Systems (ITSs). However, FLPS relies on correctly specified models. In addition, multiple latent variables, such as ability, participation, and epistemic…

Background: As people with Parkinson's experience progressive communication changes, effective, implementable speech and language therapy (SLT) interventions are needed. Process evaluations alongside pragmatic randomised controlled trials (RCTs) are of clinical value if they describe, compare and understand the implementation of trial…

Sleep disturbances are one of the most common comorbidities in autistic children and adolescence. Considering the impact of sleep disorders on development and daily functioning, it is important to know which treatments are considered effective in literature. This systematic review and meta-analysis study specifically aimed to investigate the…

Background: Children's language abilities set the stage for their education, psychosocial development and life chances across the life course. Aims: To compare the efficacy of two preschool language interventions delivered with low dosages in early years settings (EYS): Building Early Sentences Therapy (BEST) and an Adapted Derbyshire Language…

Many randomized controlled trials have investigated the role of school-based prevention interventions to reduce symptoms of anxiety and depression in young people. Systematic reviews have subsequently demonstrated a small, beneficial effect of these interventions when compared to a combined control group including usual care, no intervention, or…