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Direct linkIrene Campos-Sánchez; Eva María Navarrete-Muñoz; Dries S. Martens; Isolina Riaño-Galán; Aitana Lertxundi; Sabrina Llop; Mónica Guxens; Cristina Rodríguez-Dehli; Nerea Lertxundi; Raquel Soler-Blasco; Martine Vrijheid; Tim S. Nawrot; John Wright; Tiffany C. Yang; Rosie McEachan; Kristine Bjerve Gützkow; Vaia Lida Chatzi; Marina Vafeiadi; Mariza Kampouri; Regina Grazuleviciene; Sandra Andrusaityte; Johanna Lepeule; Desirée Valera-Gran – Journal of Attention Disorders, 2025
Objective: To explore the association between telomere length (TL) and attention deficit hyperactivity disorder (ADHD) symptoms in children at 6-12 years. Method: Data from 1,759 children belonging to the HELIX project cohorts and the Asturias, Gipuzkoa and Valencia cohorts of INMA project were included. TL was determined by blood sample using a…
Descriptors: Foreign Countries, Genetic Disorders, Attention Deficit Hyperactivity Disorder, Mothers
Michael R. Capawana; Pieter J. Vuijk; Joanna Martin; Alisha R. Pollastri; Gina A. Forchelli; Georgia G. Woscoboinik; Sonia L. Tremblay; Lauren E. Wolfe; Ellen B. Braaten; Alysa E. Doyle – Journal of Attention Disorders, 2024
Objective: We leveraged common genetic variation underlying ADHD, educational attainment (EA) and cognition (COG) to understand the nature of the Behavior Rating Inventory for Executive Functions (BRIEF) and its relationship to academic functioning. Method: Participants were 991 youth, ages 7 to 17, consecutively referred for neuropsychiatric…
Descriptors: Attention Deficit Hyperactivity Disorder, Executive Function, Child Behavior, Genetics
Kwangmi Ahn; Jenny Jean; Luke J. Norman; Philip Shaw – Journal of Attention Disorders, 2025
Objectives: Although extensive research has documented associations between Attention-Deficit/Hyperactivity Disorder (ADHD) and differences in resting-state electroencephalography (EEG) oscillatory activity, the causal nature of these relationships remains uncertain. This study aimed to determine whether there is a causal relationship between…
Descriptors: Attention Deficit Hyperactivity Disorder, Brain, Correlation, Genetics
Chanhua Li; Jiatong Deng; Weiyan Huang; Wanling Chen; Lijuan Wei; Guanghui Ran; Lili Liu; Zhongyi Li; Meiliang Liu; Dongping Huang; Shun Liu; Xiaoyun Zeng; Lijun Wang – Autism: The International Journal of Research and Practice, 2025
The physiological functions of micronutrients in neurodevelopment are well documented, but their protective effects on neurodevelopmental disorders remain controversial. We assessed the associations between micronutrients and three main neurodevelopmental disorders, that is, autism spectrum disorder (18,381 cases), attention-deficit/hyperactivity…
Descriptors: Nutrition, Child Development, Neurodevelopmental Disorders, Correlation
Ning Wang; Haibin Wang; Yu Bai; Yilu Zhao; Xiangyu Zheng; Xuping Gao; Zifeng Zhang; Li Yang – Journal of Attention Disorders, 2024
Objective: Although ADHD is highly heritable, some environmental factors contribute to its development. Given the growing evidence that gut microbiota was involved in psychiatric disorders, we aimed to identify the characteristic composition of the gut microbiota in ADHD. Methods: We recruited 47 medication-naive children and adolescents with…
Descriptors: Human Body, Microbiology, Attention Deficit Hyperactivity Disorder, Genetics
Israel Moses Gross; Yangfeifei Gao; Mary J. Lee; Alison E. Hipwell; Kate Keenan – Journal of Attention Disorders, 2024
Objective: The goal of the present study is to describe the ADHD phenotype from childhood to adolescence in Black and White girls in a community sample. Method: Primary caregivers enrolled in the population-based, longitudinal Pittsburgh Girls Study reported on girls' ADHD symptoms and impairment from ages 7 to 17; diagnostic subtypes were…
Descriptors: Attention Deficit Hyperactivity Disorder, Genetics, African Americans, Whites
Amanda M. Hughes; Fartein Ask Torvik; Elsje van Bergen; Laurie J. Hannigan; Elizabeth C. Corfield; Ole A. Andreassen; Eivind Ystrom; Helga Ask; George Davey Smith; Neil M. Davies; Alexandra Havdahl – npj Science of Learning, 2024
Children born to parents with fewer years of education are more likely to have depression, anxiety, and attention-deficit hyperactivity disorder (ADHD), but it is unclear to what extent these associations are causal. We estimated the effect of parents' educational attainment on children's depressive, anxiety, and ADHD traits at age 8 years, in a…
Descriptors: Parent Background, Educational Attainment, Depression (Psychology), Anxiety
Russell Schachar; Jennifer Crosbie – Journal of Attention Disorders, 2024
Objective: To examine the theoretical and empirical contribution of Joe Biederman and his colleagues to the understanding of executive function (EF) and ADHD. Method: We searched PubMed for references to EF in Biederman's publications and conducted a narrative review of this literature. Results: In 50 or more papers using neuropsychological tests,…
Descriptors: Attention Deficit Hyperactivity Disorder, Executive Function, Research, Etiology
Hanna Halkola; Charlotte Viktorsson; Emily J. H. Jones; Tony Charman; Terje Falck-Ytter; Giorgia Bussu – Developmental Science, 2025
Adaptive behaviour refers to the everyday skills that individuals are expected to have to function independently, based on their age and societal norms. Currently, we know little about the role of genetic and environmental factors in parent-rated adaptive behaviours in early infancy. The aim of this study was to investigate the aetiological…
Descriptors: Environmental Influences, Infant Behavior, Infants, Genetics
Marrium Mansoor; Benjamin Katz – Journal of Attention Disorders, 2023
Objective: Understanding the association between polygenic risk for ADHD and cognition throughout aging has not been widely studied. This study aimed to determine whether ADHD risk influences cognitive performance among individuals at both young-old and middle-old age. Method: Participants from the Health and Retirement Study, a biennial survey of…
Descriptors: Attention Deficit Hyperactivity Disorder, Cognitive Processes, Genetics, Executive Function
Ellen C. Masters; Kevin M. Antshel; Wendy R. Kates; Natalie Russo – Journal of Autism and Developmental Disorders, 2025
Background: Sensory processing differences are reported both in children with ADHD and in children with autism. Given the substantial overlap between autism and ADHD, the current study examined which sensory features were uniquely predictive of autistic traits after controlling for ADHD symptoms, age, IQ, and sex in a sample of children and…
Descriptors: Attention Deficit Hyperactivity Disorder, Symptoms (Individual Disorders), Sensory Integration, Autism Spectrum Disorders
Yoon-Mi Hur – Journal of Attention Disorders, 2025
Objective: The association between perceived stress (PS) and ADHD symptoms in adulthood is well established, yet the underlying mechanisms remain unclear. This study employed a genetically informative design to investigate the roles of gene-environment (GE) correlation and gene-environment interaction (G×E) in explaining this association. Three…
Descriptors: Stress Variables, Attention Deficit Hyperactivity Disorder, Adults, Genetics
Deirdre M. McCarthy; Thomas J. Spencer; Pradeep G. Bhide – Journal of Attention Disorders, 2024
Objective: We offer an overview of ADHD research using mouse models of nicotine exposure. Method: Nicotine exposure of C57BL/6 or Swiss Webster mice occurred during prenatal period only or during the prenatal and the preweaning periods. Behavioral, neuroanatomical and neurotransmitter assays were used to investigate neurobiological mechanisms of…
Descriptors: Models, Attention Deficit Hyperactivity Disorder, Smoking, Animals
Marzilli, Eleonora; Cerniglia, Luca; Tambelli, Renata; Cimino, Silvia – Child & Youth Care Forum, 2023
Background: International literature has underlined the complex interplay between genetic and environmental variables in shaping children's emotional-behavioral functioning. Objective: This study aimed to explore the dynamic relationship between children's Dopamine Transporter (DAT1) genotype and methylation, and maternal and paternal affective…
Descriptors: Play, Family Environment, Genetics, Psychopathology
Gillentine, M. A.; Berry, L. N.; Goin-Kochel, R. P.; Ali, M. A.; Ge, J.; Guffey, D.; Rosenfeld, J. A.; Hannig, V.; Bader, P.; Proud, M.; Shinawi, M.; Graham, B. H.; Lin, A.; Lalani, S. R.; Reynolds, J.; Chen, M.; Grebe, T.; Minard, C. G.; Stankiewicz, P.; Beaudet, A. L.; Schaaf, C. P. – Journal of Autism and Developmental Disorders, 2017
Chromosome 15q11q13 is among the least stable regions in the genome due to its highly complex genomic architecture. Low copy repeat elements at 15q13.3 facilitate recurrent copy number variants (CNVs), with deletions established as pathogenic and "CHRNA7" implicated as a candidate gene. However, the pathogenicity of duplications of…
Descriptors: Children, Genetics, Developmental Delays, Intellectual Disability
