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Direct linkTess Levy; Cristan Farmer; Siddharth Srivastava; Kristina Johnson; Jadyn Trayvick; Camille Brune; Alexandra Massa; Hailey Silver; Paige M. Siper; Jessica Zweifach; Danielle Halpern; Jennifer H. Foss-Feig; Jonathan A. Bernstein; Elizabeth Berry-Kravis; Craig M. Powell; Mustafa Sahin; Latha Valluripalli Soorya; Audrey Thurm; Joseph D. Buxbaum; Alexander Kolevzon – American Journal on Intellectual and Developmental Disabilities, 2025
The clinical spectrum of Phelan-McDermid syndrome (PMS) is varied, with wide-ranging degrees of intellectual disability, developmental delays, behavioral abnormalities, and medical features. Different types of genetic variation lead to PMS, and differing genotypes (e.g., size of deletion or type of variant) account for some of this variability,…
Descriptors: Genetics, Genetic Disorders, Intellectual Disability, Developmental Delays
Fouad A. Alshaban; Mohammad Aldosari; Iman Ghazal; Hawraa Al-Shammari; Saba ElHag; I. Richard Thompson; Jennifer Bruder; Hibah Shaath; Fatema Al-Faraj; Mohamed Tolefat; Assal Nasir; Eric Fombonne – Journal of Autism and Developmental Disorders, 2025
Purpose: Genetic and environmental risk factors associated with Autism Spectrum Disorders (ASD) continue to be a focus of research worldwide. Consanguinity, the cultural practice of marrying within a family, is common in cultures and societies of the Middle East, North Africa and parts of Asia. Consanguinity has been investigated as a risk factor…
Descriptors: Risk, Symptoms (Individual Disorders), Autism Spectrum Disorders, Environmental Influences
Irene Campos-Sánchez; Eva María Navarrete-Muñoz; Dries S. Martens; Isolina Riaño-Galán; Aitana Lertxundi; Sabrina Llop; Mónica Guxens; Cristina Rodríguez-Dehli; Nerea Lertxundi; Raquel Soler-Blasco; Martine Vrijheid; Tim S. Nawrot; John Wright; Tiffany C. Yang; Rosie McEachan; Kristine Bjerve Gützkow; Vaia Lida Chatzi; Marina Vafeiadi; Mariza Kampouri; Regina Grazuleviciene; Sandra Andrusaityte; Johanna Lepeule; Desirée Valera-Gran – Journal of Attention Disorders, 2025
Objective: To explore the association between telomere length (TL) and attention deficit hyperactivity disorder (ADHD) symptoms in children at 6-12 years. Method: Data from 1,759 children belonging to the HELIX project cohorts and the Asturias, Gipuzkoa and Valencia cohorts of INMA project were included. TL was determined by blood sample using a…
Descriptors: Foreign Countries, Genetic Disorders, Attention Deficit Hyperactivity Disorder, Mothers
Hannah R. Benavidez; Margaret Johansson; Elizabeth Jones; Hannah Rea; Evangeline C. Kurtz-Nelson; Conor Miles; Alana Whiting; Curtis Eayrs; Rachel Earl; Raphael A. Bernier; Evan E. Eichler; Emily Neuhaus – Journal of Autism and Developmental Disorders, 2025
Specialized multidisciplinary supports are important for long-term outcomes for autistic youth. Although family and child factors predict service utilization in autism, little is known with respect to youth with rare, autism-associated genetic variants, who frequently have increased psychiatric, developmental, and behavioral needs. We investigate…
Descriptors: Predictor Variables, Intervention, Youth, Autism Spectrum Disorders
Pasquale Cardellicchio; Sara Borgomaneri – npj Science of Learning, 2025
The consolidation process stabilizes a new initially labile memory. This consolidation could operate on a shorter timescale during wakefulness after initial motor learning. Within micro-offline learning states, sequences of simple individual actions learned through interleaved practice are condensed into a unified skill through a time-dependent…
Descriptors: Brain, Brain Hemisphere Functions, Genetics, Cognitive Processes
Gabriela Perez-Garcia; Andrea Gomez Barillas; Renata Mendizábal-Cabrera; Danilo Alvarez; Brooke M. Ramay; Nikolina Walas; Jay P. Graham – Field Methods, 2025
In many countries, soiled toilet paper is placed in trash bins rather than flushed down the toilet. We investigated the use of soiled toilet paper in Guatemalan markets to surveil for pathogenic sequence types (STs) of "E. coli" and third generation cephalosporin-resistant "E. coli" (3GCR-EC). We collected used toilet paper…
Descriptors: Sanitation, Diseases, Pathology, Sanitary Facilities
Kwangmi Ahn; Jenny Jean; Luke J. Norman; Philip Shaw – Journal of Attention Disorders, 2025
Objectives: Although extensive research has documented associations between Attention-Deficit/Hyperactivity Disorder (ADHD) and differences in resting-state electroencephalography (EEG) oscillatory activity, the causal nature of these relationships remains uncertain. This study aimed to determine whether there is a causal relationship between…
Descriptors: Attention Deficit Hyperactivity Disorder, Brain, Correlation, Genetics
Tyler M. Moore; Katherine C. Lopez; J. Cobb Scott; Jack C. Lennon; Akira Di Sandro; Eirini Zoupou; Alesandra Gorgone; Monica E. Calkins; Daniel H. Wolf; Joseph W. Kable; Kosha Ruparel; Raquel E. Gur; Ruben C. Gur – Journal of Psychoeducational Assessment, 2025
The Penn Computerized Neurocognitive Battery (CNB) is a collection of tests validated using neuroimaging, genetics, and other criteria. An updated version of the CNB was constructed in which all tests were converted to either computerized adaptive (CAT) or abbreviated forms. In a mixed community/clinical sample (N = 307; mean age = 25.9 years;…
Descriptors: Computer Assisted Testing, Cognitive Ability, Genetics, Adaptive Testing
Alaina M. Di Dio; Elizabeth A. Shewark; Daniel Thaler; S. Alexandra Burt – JCPP Advances, 2025
Background: Lower parental nurturance is consistently associated with higher levels of youth antisocial behavior (ASB), but the etiology of this association remains unclear. To fill this gap, we employed a twin differences approach to illuminate the environmental and genetic origins of the association between parental nurturance and children's…
Descriptors: Parenting Styles, Parent Child Relationship, Antisocial Behavior, Twins
Download full textKhusnun Nisa Muftifah; Wolly Candramila; Anisyah Yuniarti – Pedagogical Research, 2025
Genetics is a fundamental topic in Biology, yet its abstract nature presents challenges in the learning process. Effective teaching of genetics concepts requires appropriate instructional approaches to facilitate student understanding. The success of learning outcomes depends on various components, including teachers, students, learning…
Descriptors: Foreign Countries, Teaching Methods, Science Instruction, Genetics
Ming-Mei Chang – Biochemistry and Molecular Biology Education, 2025
Laboratory experience is vital to undergraduate science education. It allows students to observe and conduct engaging experiments to enhance their skills and literacy, helps them retain knowledge, and deepens their understanding of related content covered in lectures. This paper reports a 4-week undergraduate laboratory exercise on…
Descriptors: Undergraduate Students, Science Laboratories, Genetics, Laboratory Experiments
Andrew J. Tonsager; Laurie A. Stargell – Biochemistry and Molecular Biology Education, 2025
CRISPR-Cas9 technology is an established, powerful tool for genome editing through the ability to target specific DNA sequences of interest for introduction of desired genetic modifications. CRISPR-Cas9 is utilized for a variety of purposes, ranging from a research molecular biology tool to treatment for human diseases. Due to its prominence…
Descriptors: Undergraduate Students, Student Research, Scientific Research, Genetics
Francesco Sessa; Mario Chisari; Massimiliano Esposito; Michele Ahmed Antonio Karaboue; Monica Salerno; Giuseppe Cocimano – Journal of Academic Ethics, 2025
Ethical, legal and social implications (ELSIs) in forensic genetics investigations (FGIs) also involve conducting a careful assessment of the potential benefits and responsible use of genetic information. FGIs have become an invaluable tool in solving crimes and identifying individuals in various legal and investigative contexts. Moreover,…
Descriptors: Genetics, Crime, Ethics, Investigations
Catherine Mick; Don Lee; Leah Sandall; Katherine Frels; Yufeng Ge – Natural Sciences Education, 2025
Traditional phenotyping methods are labor-intensive, time-consuming, and often destructive measurements that describe plant traits. Technology allows the advancement of sensor-based phenotype data to be collected digitally. This area of work is called high-throughput phenotyping (HTP). HTP is rapid, non-destructive, and non-invasive. The effective…
Descriptors: Plants (Botany), Genetics, Open Educational Resources, Technology Integration
Julia Wynn; Anna Karlsen; Benjamin Huber; Alina Levine; Amanie Salem; L. Casey White; Marti Luby; Ekaterina Bezborodko; Sabrina Xiao; Wendy K. Chung; Robert L. Klitzman; Paul S. Appelbaum – Journal of Autism and Developmental Disorders, 2025
Genetic testing is recommended as part of an autism assessment, and most parents support genetic testing for their minor children. However, the impact on parents of receiving a monogenetic/ copy number variant diagnosis for autism in their child is not well understood. To explore this, we surveyed and interviewed parents of children in the SPARK…
Descriptors: Genetics, Screening Tests, Parent Attitudes, Parent Child Relationship
