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Direct linkKwangmi Ahn; Jenny Jean; Luke J. Norman; Philip Shaw – Journal of Attention Disorders, 2025
Objectives: Although extensive research has documented associations between Attention-Deficit/Hyperactivity Disorder (ADHD) and differences in resting-state electroencephalography (EEG) oscillatory activity, the causal nature of these relationships remains uncertain. This study aimed to determine whether there is a causal relationship between…
Descriptors: Attention Deficit Hyperactivity Disorder, Brain, Correlation, Genetics
Eugene Merzon; Ariel Israel; Beth Krone; Shani Medvejer; Shira Cohen; Ilan Green; Avivit Golan-Cohen; Shlomo Vinker; Stephen V. Faraone; Jeffrey H. Newcorn; Shai Ashkenazi; Abraham Weizman; Iris Manor – Journal of Attention Disorders, 2024
Objective: There is growing evidence of involvement of inflammatory mechanisms in ADHD. Previous studies found significantly higher rates of ADHD among children with FMF. The present study examined the rate of exposure to FMF in children with a later (within a 5-year period) diagnosis of ADHD compared to non-ADHD children. Methods: A…
Descriptors: Attention Deficit Hyperactivity Disorder, Diseases, Physiology, Genetic Disorders
Chanhua Li; Jiatong Deng; Weiyan Huang; Wanling Chen; Lijuan Wei; Guanghui Ran; Lili Liu; Zhongyi Li; Meiliang Liu; Dongping Huang; Shun Liu; Xiaoyun Zeng; Lijun Wang – Autism: The International Journal of Research and Practice, 2025
The physiological functions of micronutrients in neurodevelopment are well documented, but their protective effects on neurodevelopmental disorders remain controversial. We assessed the associations between micronutrients and three main neurodevelopmental disorders, that is, autism spectrum disorder (18,381 cases), attention-deficit/hyperactivity…
Descriptors: Nutrition, Child Development, Neurodevelopmental Disorders, Correlation
Zequn Zheng; Dihui Cai – Journal of Attention Disorders, 2025
Background: While observational studies have established a connection between attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and heightened risk for cardiovascular diseases (CVD), the causal relationships are not well-defined. This study is designed to examine the causality between ASD, ADHD, and CVD risk as well…
Descriptors: Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorders, Heart Disorders, Correlation
Yoon-Mi Hur – Journal of Attention Disorders, 2025
Objective: The association between perceived stress (PS) and ADHD symptoms in adulthood is well established, yet the underlying mechanisms remain unclear. This study employed a genetically informative design to investigate the roles of gene-environment (GE) correlation and gene-environment interaction (G×E) in explaining this association. Three…
Descriptors: Stress Variables, Attention Deficit Hyperactivity Disorder, Adults, Genetics
Deirdre M. McCarthy; Thomas J. Spencer; Pradeep G. Bhide – Journal of Attention Disorders, 2024
Objective: We offer an overview of ADHD research using mouse models of nicotine exposure. Method: Nicotine exposure of C57BL/6 or Swiss Webster mice occurred during prenatal period only or during the prenatal and the preweaning periods. Behavioral, neuroanatomical and neurotransmitter assays were used to investigate neurobiological mechanisms of…
Descriptors: Models, Attention Deficit Hyperactivity Disorder, Smoking, Animals
Marzilli, Eleonora; Cerniglia, Luca; Tambelli, Renata; Cimino, Silvia – Child & Youth Care Forum, 2023
Background: International literature has underlined the complex interplay between genetic and environmental variables in shaping children's emotional-behavioral functioning. Objective: This study aimed to explore the dynamic relationship between children's Dopamine Transporter (DAT1) genotype and methylation, and maternal and paternal affective…
Descriptors: Play, Family Environment, Genetics, Psychopathology
Zuhal Koc Apaydin; Meryem Kasak; Ozlem Karakaya; Hakan Ogutlu; Mustafa Ugurlu; Fiona McNicholas – Journal of Attention Disorders, 2025
Objective: This study aimed to investigate the relationship between Cognitive Disengagement Syndrome (CDS) symptoms in children/adolescents and their parents within the Turkish population, examining the association with co-occurring ADHD symptoms, peer/social relationships, and total difficulties. Method: The study included 229 parents aged 18 to…
Descriptors: Children, Adolescents, Parents, Symptoms (Individual Disorders)
Gustavson, Kristin; Torvik, Fartein A.; Eilertsen, Espen M.; Ask, Helga; McAdams, Tom A.; Hannigan, Laurie J.; Reichborn-Kjennerud, Ted; Ystrom, Eivind; Gjerde, Line C. – Developmental Psychology, 2021
Children with attention deficit hyperactivity disorder (ADHD) often experience co-occurring emotional problems. ADHD with this comorbidity is associated with poorer outcomes than ADHD without comorbidity. Better understanding of the etiology of comorbidity could improve prevention of negative outcomes for children with ADHD. The sample consisted…
Descriptors: Attention Deficit Hyperactivity Disorder, Emotional Problems, Comorbidity, Twins
Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Donati, Georgina; Dumontheil, Iroise; Meaburn, Emma L. – Mind, Brain, and Education, 2019
Individual differences in executive functions (EF) are heritable and predictive of academic attainment (AA). However, little is known about genetic contributions to EFs or their genetic relationship with AA and intelligence. We conducted genome-wide association analyses for processing speed (PS) and the latent EF measures of working memory (WM)…
Descriptors: Genetics, Executive Function, Educational Attainment, Individual Differences
Myers, Lynnea; van't Westeinde, Annelies; Kuja-Halkola, Ralf; Tammimies, Kristiina; Bölte, Sven – Journal of Autism and Developmental Disorders, 2018
The second to fourth digit (2D:4D) ratio is of interest in autism spectrum disorder (ASD). Studies on the relationship of this ratio with other neurodevelopmental disorders (NDDs) are lacking. Investigating the association between the ratio and NDDs in twins can provide insight into genetic and/or environmental factors driving the ratio. Hand…
Descriptors: Twins, Autism, Pervasive Developmental Disorders, Correlation
LaBianca, S.; Pagsberg, A. K.; Jakobsen, K. D.; Demur, A. B.; Bartalan, M.; LaBianca, J.; Werge, T. – Journal of Autism and Developmental Disorders, 2018
Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with…
Descriptors: Pervasive Developmental Disorders, Autism, Attention Deficit Hyperactivity Disorder, Correlation
Merker, Sören; Reif, Andreas; Ziegler, Georg C.; Weber, Heike; Mayer, Ute; Ehlis, Ann-Christine; Conzelmann, Annette; Johansson, Stefan; Müller-Reible, Clemens; Nanda, Indrajit; Haaf, Thomas; Ullmann, Reinhard; Romanos, Marcel; Fallgatter, Andreas J.; Pauli, Paul; Strekalova, Tatyana; Jansch, Charline; Vasquez, Alejandro Arias; Haavik, Jan; Ribasés, Marta; Ramos-Quiroga, Josep Antoni; Buitelaar, Jan K.; Franke, Barbara; Lesch, Klaus-Peter – Journal of Child Psychology and Psychiatry, 2017
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental disorder with profound cognitive, behavioral, and psychosocial impairments with persistence across the life cycle. Our initial genome-wide screening approach for copy number variants (CNVs) in ADHD implicated a duplication of…
Descriptors: Attention Deficit Hyperactivity Disorder, Neurological Impairments, Genetic Disorders, Physiology
Daucourt, Mia C.; Erbeli, Florina; Little, Callie W.; Haughbrook, Rasheda; Hart, Sara A. – Scientific Studies of Reading, 2020
According to the Multiple Deficit Model, comorbidity results when the genetic and environmental risk factors that increase the liability for a disorder are domain-general. In order to explore the role of domain-general etiological risk factors in the co-occurrence of learning-related difficulties, the current meta-analysis compiled 38 studies of…
Descriptors: Learning Problems, Attention Deficit Hyperactivity Disorder, Reading Skills, Mathematics Skills
