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Direct linkCochran, Lisa; Welham, Alice; Oliver, Chris; Arshad, Adam; Moss, Joanna F. – Journal of Autism and Developmental Disorders, 2019
Age-related behavioural change in Cornelia de Lange syndrome is poorly understood. We report a 7 year follow-up study of adaptive behaviour, autism spectrum disorder symptomatology, language skills and behavioural characteristics in 30 individuals with Cornelia de Lange syndrome, compared with 18 individuals with Cri du Chat syndrome. The…
Descriptors: Behavior Change, Followup Studies, Autism, Pervasive Developmental Disorders
Assessment of Pretend Play in Prader-Willi Syndrome: A Direct Comparison to Autism Spectrum Disorder
Zyga, Olena; Russ, Sandra; Ievers-Landis, Carolyn E.; Dimitropoulos, Anastasia – Journal of Autism and Developmental Disorders, 2015
Children with Prader-Willi syndrome (PWS) are at risk for autism spectrum disorder (ASD), including pervasive social deficits. While play impairments in ASD are well documented, play abilities in PWS have not been evaluated. Fourteen children with PWS and ten children with ASD were administered the Autism Diagnostic Observation Schedule (ADOS)…
Descriptors: Genetic Disorders, Mental Retardation, Autism, Pervasive Developmental Disorders
Klusek, J.; Martin, G. E.; Losh, M. – Journal of Intellectual Disability Research, 2014
Background: Prior research suggests that 60-74% of males and 16-45% of females with fragile X syndrome (FXS) meet criteria for autism spectrum disorder (ASD) in research settings. However, relatively little is known about the rates of clinical diagnoses in FXS and whether such diagnoses are consistent with those performed in a research setting…
Descriptors: Genetic Disorders, Pervasive Developmental Disorders, Autism, Clinical Diagnosis
Russo-Ponsaran, Nicole M.; Berry-Kravis, Elizabeth; McKown, Clark A.; Lipton, Meryl – Journal of Mental Health Research in Intellectual Disabilities, 2014
Fragile X syndrome (FXS) is a well-described inherited cause of intellectual disability and the most common known genetic cause of autism. Social deficits in girls with FXS are not well understood. To better understand barriers to social functioning that may contribute to mental health outcomes, we administered a theoretically based social…
Descriptors: Females, Genetic Disorders, Cognitive Processes, Social Development
Martin, Gary E.; Losh, Molly; Estigarribia, Bruno; Sideris, John; Roberts, Joanne – International Journal of Language & Communication Disorders, 2013
Background: Fragile X syndrome (FXS) and Down syndrome (DS) are the two leading genetic causes of intellectual disability, and FXS is the most common known genetic condition associated with autism. Both FXS and DS are associated with significant language impairment, but little is known about expressive language across domains over time or the role…
Descriptors: Expressive Language, Vocabulary, Syntax, Pragmatics
Moss, Jo; Howlin, Patricia; Magiati, Iliana; Oliver, Chris – Journal of Child Psychology and Psychiatry, 2012
Background: The prevalence of autism spectrum disorder (ASD) symptomatology is comparatively high in Cornelia de Lange syndrome (CdLS). However, the profile and developmental trajectories of these ASD characteristics are potentially different to those observed in individuals with idiopathic ASD. In this study we examine the ASD profile in CdLS in…
Descriptors: Autism, Pervasive Developmental Disorders, Genetic Disorders, Mental Retardation
