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An Undergraduate Research Experience in CRISPR-Cas9 Mediated Eukaryotic Genome Editing to Teach Fundamental Biochemistry Techniques
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Andrew J. Tonsager; Laurie A. Stargell – Biochemistry and Molecular Biology Education, 2025
CRISPR-Cas9 technology is an established, powerful tool for genome editing through the ability to target specific DNA sequences of interest for introduction of desired genetic modifications. CRISPR-Cas9 is utilized for a variety of purposes, ranging from a research molecular biology tool to treatment for human diseases. Due to its prominence…
Descriptors: Undergraduate Students, Student Research, Scientific Research, Genetics
An Online Interactive Map of Human Metabolic Pathways and Associated Genetic Disorders as a Tool for the Biochemistry Classroom
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Hannah K. Parker; Beth Zizzamia; Julie A. Pollock – Journal of Chemical Education, 2025
In a typical undergraduate biochemistry course, two main educational objectives include (1) understanding and applying how genetic mutations can influence protein structure and function, and (2) examining metabolic pathways of biomolecules to study cellular storage and fuel. Many times, these topics can seem disparate to students; therefore, we…
Descriptors: Undergraduate Students, College Science, Science Instruction, Biochemistry
Linking Science and Industry: Influence of Scientific Research on Technological Innovation through Patent Citations
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Pablo Dorta-González; Alejandro Rodríguez-Caro; María Isabel Dorta-González – Research Evaluation, 2025
This study explores the connection between patent citations and scientific publications across six fields: Biochemistry, Genetics, Pharmacology, Engineering, Mathematics, and Physics. Analysing 117,590 papers from 2014 to 2023, the research emphasizes how publication year, open access (OA) status, and discipline influence patent citations. Openly…
Descriptors: Intellectual Property, Scientific Research, Publications, Citations (References)
Evaluating Patients with Mucopolysaccharidosis Type III: A Scoping Review on Diagnostic and Follow-Up Approaches
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Agustina Sabino Romagnoli; Letícia Nunes Campos; Daniel Fernandez-Guzman; Sofia Wagemaker; Federico Fernandez Zelcer; Carlos Stegmann; Carina F. Argüelles; Laura F. Sosa; Ayla Gerk; Jorgelina Stegmann – Journal of Applied Research in Intellectual Disabilities, 2025
Background: Mucopolysaccharidosis type III (MPS III) is a rare lysosomal storage disease with systemic complications. This scoping review aimed to synthesise evidence regarding methods to diagnose and monitor MPS III. Methods: We searched 10 databases for English and Spanish citations published from 2017 to 2022. Our study focused on human-based…
Descriptors: Clinical Diagnosis, Patients, Genetic Disorders, Diseases
An Idea to Explore: Analysis of Datasets on Diseases Associated with Protein Glycosylation as a Pedagogical Approach Using Free Software to Teach the Biochemistry of Diseases
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Abhiru Chathurma Elaphatha; Meran Keshawa Ediriweera – Biochemistry and Molecular Biology Education, 2025
Glycosylation is a biologically significant post-translational modification (PTM) of proteins that involves the covalent attachment of a sugar molecule (a glycan) to a peptide sequence, resulting in the formation of glycoproteins. Glycomics and glycoproteomics involve the complete mapping of glycans of a cell, tissue, or organism.…
Descriptors: Data Analysis, Diseases, Computer Software, Computer Uses in Education
Incorporation of NUPACK-Based Simulation into Classroom and Laboratory Teaching of Nucleic Acids Hybridization for Undergraduate Biochemistry
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Jinglin Fu; Anthony Monte Carlo; Doris Zheng – Journal of Chemical Education, 2025
The COVID-19 pandemic has accelerated the shift from traditional in-person teaching to remote and online learning, necessitating a more adaptable educational platform to serve the diverse needs of students. Transforming hands-on "wet lab" activities into virtual "dry lab" exercises can promote a more accessible and flexible…
Descriptors: Undergraduate Students, College Science, Science Education, Biochemistry