Science should provide students an accurate and contemporary education on genetic influence, particularly how it impacts trait variability and developmental norms. Stories involving familial, racial, and sexual differences routinely appear in the popular media and sales of over-the-counter genetic tests are mounting. Unfortunately, research…

The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…

Transcription is the critical first step in expressing a gene, during which an RNA polymerase (RNAP) synthesizes an RNA copy of one strand of the DNA that encodes a gene. Here we describe a laboratory experiment that uses a single assay to probe two important steps in transcription: (1) RNAP binding to DNA, and (2) the transcriptional activity of…

In 1900, three botanists claimed they had found regularities in inheritance, which soon would be known as Mendel's Laws, without knowing the work of Gregor Mendel or of each other. Their claims of independent (re)discovery have been thoroughly studied during the past decades, with various outcomes. The case is still of interest today as it offers…

It is 157 years since Mendel presented his results on hybridisation in peas to the Brünn Society for Natural Science. The discipline of genetics has dramatically changed since then, with technological advancements revealing multifactorial causation and trait variability. Whilst none of this complexity featured in the discovery of classical…

In the context of England, secondary biology education is dominated by sub-organismal systems, such as physiology, often to the detriment of evolution & ecology and impeding an integrated understanding of biology. This paper proposes a framework that teachers could use to help them consider how the learning of physiological and developmental…

Despite a decline in sexist language, traditional gender beliefs remain embedded in the scientific literature on reproductive biology and consequently continue to distort knowledge, encumber the learning process, and reinforce gender essentialism. This article analyzes the enduring force of gender stereotypes in Italian middle school science…

Nowadays, novel Biochemistry lab techniques are being introduced at a very fast pace in scientific research. This requires development of new labs for undergraduate Biochemistry courses to equip the students with up-to-date techniques. However, the time limit of Biochemistry labs for undergraduate students represents a major obstacle. This article…

Biology is a data-driven discipline facilitated greatly by computer programming skills. This article describes an introductory experiential programming activity that can be integrated into distance learning environments. Students are asked to develop their own Python programs to identify the nature of alleles linked to disease. This activity…

We have designed and tested an exercise to detect misconceptions among students about meiosis, a fundamental concept in genetics. A total of 30 students responded to a questionnaire, all of whom were in the fifth semester of the Biology bachelor's degree program offered by the Faculty of Science of the National Autonomous University of Mexico. Our…

We will attempt a synthesis from various research perspectives that have analyzed the alterations that knowledge inevitably goes through while percolating into classroom activities. We will try to identify some of their causes and will illustrate them with examples in genetics. First, we will discuss some research on knowledge transformation when…

We review software for exploring biological evolution from a fun and educational perspective. Our goal is to provide a background explanation of the methods used, terminology, and user experience, and learning outcomes of desktop and mobile evolutionary simulators. Freeware and commercial programs are detailed, with a discussion of how certain…

Just before his death in 1970, John Scopes claimed that his famous trial "had no other effect upon my family" than his sister Lela losing her teaching job in Paducah, Kentucky. He was wrong. My interviews with John Scopes's family members and descendants -- most of whom have never talked about their famous relative until now -- reveal…

Teaching the Genome Generation (TtGG) is a teacher professional development program and set of high school biology lessons that support interwoven classroom instruction of molecular genetics, bioinformatics, and bioethics. Participating teachers from across New England implement the modular elements of program at a high rate in a variety of…

Classroom observation protocols can provide an exceedingly rich form of data. However, this is a double-edged sword, as researchers often struggle to take full advantage of the detailed data outputs. In this essay, we introduce a new approach to the analysis of classroom observation data, termed "classroom as genome" (CAG). We illustrate…