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Direct linkPhillips, Ashley N.; Maricle, Denise E. – Journal of the American Academy of Special Education Professionals, 2021
Multiple sclerosis is an inflammatory autoimmune disease that attacks the central nervous system through the destruction of myelin. Frequently cited symptoms include cognitive impairment as a hallmark repercussion, neuropsychological executive dysfunction, and psychosocial disturbances, such as affective disorders and fatigue. Other symptomatology…
Descriptors: Neurological Impairments, Physical Disabilities, Cognitive Ability, Symptoms (Individual Disorders)
Raspa, Melissa; Bann, Carla M.; Gwaltney, Angela; Benke, Timothy A.; Fu, Cary; Glaze, Daniel G.; Haas, Richard; Heydemann, Peter; Jones, Mary; Kaufmann, Walter E.; Lieberman, David; Marsh, Eric; Peters, Sarika; Ryther, Robin; Standridge, Shannon; Skinner, Steven A.; Percy, Alan K.; Neul, Jeffrey L. – American Journal on Intellectual and Developmental Disabilities, 2020
Rett syndrome (RTT) is a neurodevelopmental disorder that primarily affects females. Recent work indicates the potential for disease modifying therapies. However, there remains a need to develop outcome measures for use in clinical trials. Using data from a natural history study (n = 1,075), we examined the factor structure, internal consistency,…
Descriptors: Genetic Disorders, Psychometrics, Psychomotor Skills, Physical Disabilities
Libertus, Melissa E.; Feigenson, Lisa; Halberda, Justin; Landau, Barbara – Developmental Science, 2014
All numerate humans have access to two systems of number representation: an exact system that is argued to be based on language and that supports formal mathematics, and an Approximate Number System (ANS) that is present at birth and appears independent of language. Here we examine the interaction between these two systems by comparing the…
Descriptors: Congenital Impairments, Genetic Disorders, Mental Retardation, Number Systems
Goodrich-Hunsaker, Naomi J.; Wong, Ling M.; McLennan, Yingratana; Srivastava, Siddharth; Tassone, Flora; Harvey, Danielle; Rivera, Susan M.; Simon, Tony J. – Brain and Cognition, 2011
The high frequency of the fragile X premutation in the general population and its emerging neurocognitive implications highlight the need to investigate the effects of the premutation on lifespan cognitive development. Until recently, cognitive function in fragile X premutation carriers (fXPCs) was presumed to be unaffected by the mutation. Here…
Descriptors: Young Adults, Cognitive Development, Genetic Disorders, Females
Berry-Kravis, Elizabeth; Raspa, Melissa; Loggin-Hester, Lisa; Bishop, Ellen; Holiday, David; Bailey, Donald B., Jr. – American Journal on Intellectual and Developmental Disabilities, 2010
A national survey of caregivers of individuals with fragile X syndrome addressed characteristics of epilepsy and co-occurring conditions. Of the 1,394 individuals (1,090 males and 304 females) with the full mutation, 14% of males and 6% of females reported seizures. Seizures were more often partial, began between ages 4 and 10 years, and were…
Descriptors: Seizures, Caregivers, National Surveys, Disabilities
Jauhari, Prashant; Boggula, Raju; Bhave, Anupama; Bhargava, Roli; Singh, Chandrakanta; Kohli, Neera; Yadav, Rajesh; Kumar, Rashmi – Developmental Medicine & Child Neurology, 2011
Aim: To study the aetiology of intellectual disability in patients presenting to hospital and the diagnostic yield of a standardized examination. Method: Over a 1-year period, the first three children presenting to the paediatric outpatients department (OPD) on 2 selected weekdays with developmental delay, suspected intellectual disability, or…
Descriptors: Maturity (Individuals), Mental Retardation, Seizures, Patients
Vlachou, Maria; Andreou, Eleni; Botsoglou, Kafenia; Didaskalou, Eleni – Educational Psychology Review, 2011
Bullying in schools has been identified as a serious and complex worldwide problem associated with negative short- and long-term effects on children's psychosocial adjustment (Smith 1999; Ttofi and Farrington, "Aggressive Behav" 34(4):352-368, 2008). Entering kindergarten is a crucial developmental step in many children's lives mainly because it…
Descriptors: Evidence, Bullying, Preschool Children, Age Differences
Olson, Richard K.; Keenan, Janice M.; Byrne, Brian; Samuelsson, Stefan; Coventry, William L.; Corley, Robin; Wadsworth, Sally J.; Willcutt, Erik G.; DeFries, John C.; Pennington, Bruce F.; Hulslander, Jacqueline – Scientific Studies of Reading, 2011
Genetic and environmental relations between vocabulary and reading skills were explored longitudinally from preschool through Grades 2 and 4. At preschool there were strong shared-environment and weak genetic influences on both vocabulary and print knowledge but substantial differences in their source. Separation of etiology for vocabulary and…
Descriptors: Reading Comprehension, Genetics, Word Recognition, Etiology
Stinton, Chris; Elison, Sarah; Howlin, Patricia – American Journal on Intellectual and Developmental Disabilities, 2010
Although many researchers have investigated emotional and behavioral difficulties in individuals with Williams syndrome, few have used standardized diagnostic assessments. We examined mental health problems in 92 adults with Williams syndrome using the Psychiatric Assessment Schedule for Adults with Developmental Disabilities--PAS-ADD (Moss,…
Descriptors: Developmental Disabilities, Mental Health, Depression (Psychology), Mental Disorders
Urbanowicz, Anna; Downs, Jenny; Bebbington, Ami; Jacoby, Peter; Girdler, Sonya; Leonard, Helen – Research in Autism Spectrum Disorders, 2011
This study assessed factors that could influence equipment and respite services use among Australian families caring for a girl/woman with Rett syndrome and examined relationships between use of these resources and the health of female caregivers. Data was sourced from questionnaires completed by families (n=170) contributing to the Australian…
Descriptors: Mothers, Physical Health, Caregivers, Respite Care
May, Michael E.; Srour, Ali; Hedges, Lora K.; Lightfoot, David A.; Phillips, John A., III; Blakely, Randy D.; Kennedy, Craig H. – American Journal on Intellectual and Developmental Disabilities, 2009
A functional polymorphism in the promoter of the gene encoding monoamine oxidase A has been associated with problem behavior in various populations. We examined the association of MAOA alleles in adult males with intellectual/developmental disabilities with and without established histories of problem behavior. These data were compared with a…
Descriptors: Developmental Disabilities, Males, Genetic Disorders, Mental Retardation
Desjardins, Richard; Warnke, Arne Jonas – OECD Publishing (NJ1), 2012
The relationship between ageing and skills is becoming an important policy issue, not least in the context of population ageing. Data from the Programme for the International Assessment of Adult Competencies (PIAAC) will potentially add considerably to the understanding of the relationship between ageing and foundation skills. In particular, the…
Descriptors: Multivariate Analysis, Foreign Countries, Profiles, Adult Literacy
Howell, Peter – Clinical Linguistics & Phonetics, 2008
Van Borsel, Dor, and Rondal (2007) examined the speech of seven boys and two young male adults with fragile X syndrome and considered whether their speech was comparable to that reported in the developmental stuttering literature. They listed five criteria which led them to conclude that the speech patterns of speakers with fragile X syndrome…
Descriptors: Speech Impairments, Stuttering, Genetics, Mental Retardation
McDuffie, Andrea; Abbeduto, Leonard; Lewis, Pamela; Kover, Sara; Kim, Jee-Seon; Weber, Ann; Brown, W. Ted – American Journal on Intellectual and Developmental Disabilities, 2010
The Autism Diagnostic Interview-Revised (ADI-R) was used to examine diagnostic profiles and age-related changes in autism symptoms for a group of verbal children and adolescents who had fragile X syndrome, with and without autism. After controlling for nonverbal IQ, we found statistically significant between-group differences for lifetime and…
Descriptors: Autism, Interests, Intelligence Quotient, Interaction
Sherman, Stephanie L.; Allen, Emily G.; Bean, Lora H.; Freeman, Sallie B. – Mental Retardation and Developmental Disabilities Research Reviews, 2007
Down syndrome (DS) is the most commonly identified genetic form of mental retardation and the leading cause of specific birth defects and medical conditions. Traditional epidemiological studies to determine the prevalence, cause, and clinical significance of the syndrome have been conducted over the last 100 years. DS has been estimated to occur…
Descriptors: Incidence, Ethnic Groups, Child Health, Down Syndrome
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