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Concomitant Medication Use in Children with Autism Spectrum Disorder: Data from the Autism Biomarkers Consortium for Clinical Trials
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Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Shorter Average Look Durations to Dynamic Social Stimuli Are Associated with Higher Levels of Autism Symptoms in Young Autistic Children
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Major, Samantha; Isaev, Dmitry; Grapel, Jordan; Calnan, Todd; Tenenbaum, Elena; Carpenter, Kimberly; Franz, Lauren; Howard, Jill; Vermeer, Saritha; Sapiro, Guillermo; Murias, Michael; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2022
Prior eye-tracking studies involving autistic individuals have focused on total looking time or proportion of looking time to key regions of interest. These studies have not examined another important feature, the ability to sustain attention to stimuli. In particular, the ability to sustain attention to a dynamic social stimulus might reflect…
Descriptors: Eye Movements, Autism Spectrum Disorders, Attention, Visual Stimuli
Gastrointestinal Problems Are Associated with Increased Repetitive Behaviors but Not Social Communication Difficulties in Young Children with Autism Spectrum Disorders
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Chakraborty, Payal; Carpenter, Kimberly L. H.; Major, Samantha; Deaver, Megan; Vermeer, Saritha; Herold, Brianna; Franz, Lauren; Howard, Jill; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2021
Individuals with autism spectrum disorder are more likely than typically developing individuals to experience a range of gastrointestinal abnormalities, including chronic diarrhea, constipation, food sensitivities, and abdominal pain. These gastrointestinal symptoms have been associated with higher levels of irritability and aggressive behavior,…
Descriptors: Autism, Pervasive Developmental Disorders, Human Body, At Risk Persons
Measuring Repetitive Behaviors as a Treatment Endpoint in Youth with Autism Spectrum Disorder
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Scahill, Lawrence; Aman, Michael G.; Lecavalier, Luc; Halladay, Alycia K.; Bishop, Somer L.; Bodfish, James W.; Grondhuis, Sabrina; Jones, Nancy; Horrigan, Joseph P.; Cook, Edwin H.; Handen, Benjamin L.; King, Bryan H.; Pearson, Deborah A.; McCracken, James T.; Sullivan, Katherine Anne; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2015
Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized…
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Problems, Repetition